Gonadoblastoma screening
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Gonadoblastoma Microchapters |
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Risk calculators and risk factors for Gonadoblastoma screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
There is insufficient evidence to recommend routine screening for gonadoblastoma. However, patients with XY gonadal abnormalities should be followed using sonography starting at age 2, every six months, until the gonads are removed.
Screening
- There is insufficient evidence to recommend routine screening for gonadoblastoma.
- However, patients with XY gonadal abnormalities should be followed using sonography starting at age 2, every six months, until the gonads are removed.[1][2]
- Although very uncommon, gonadoblastoma may develop in phenotypically and genotypically normal individuals.
- In these individuals, the affected gonads must be removed due to the risk of gonadoblastoma conversion to dysgerminoma.
- Close monitoring with imaging studies also recommended for the contralateral gonads if it is preserved.
References
- ↑ "Yen & Jaffe's Reproductive Endocrinology | ScienceDirect".
- ↑ Hatano T, Yoshino Y, Kawashima Y, Shirai H, Iizuka N, Miyazawa Y, Sakata A, Onishi T (March 1999). "Case of gonadoblastoma in a 9-year-old boy without physical abnormalities". Int. J. Urol. 6 (3): 164–6. PMID 10226831.