Crush syndrome
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| Crush syndrome Classification and external resources | |
| ICD-10 | T79.5 |
|---|---|
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch. Crush syndrome (also traumatic rhabdomyolysis or Bywaters' syndrome) is a serious medical condition characterized by major shock and renal failure following a crushing injury to skeletal muscle. Cases commonly occur in catastrophes such as earthquakes or war, where victims have been trapped under fallen masonry (the syndrome was discovered by British physician Eric Bywaters in patients during the 1941 London Blitz).
It is a reperfusion injury that appears after the release of the crushing pressure. The mechanism is believed to be the release into the bloodstream of toxic chemicals - notably myoglobin, potassium and phosphorus - that are the products of rhabdomyolysis (the breakdown of skeletal muscle damaged by ischemic conditions).
The specific action on the kidneys is not fully understood, but may be due in part to nephrotoxic metabolites of myoglobin.
References
- Bywaters EG, Beall D. Crush injuries with impairment of renal function. Br Med J 1941;1:427-32
- Sever MS et al. Management of Crush-Related Injuries after Disasters. NEJM 2006;354:1052-63
Consequences of external causes (T15-T35, T66-T98, 930-959, 990-995) | |
|---|---|
| General external causes | Foreign body - Burn - Frostbite |
| Other external causes | Radiation poisoning - Hyperthermia - Hypothermia - Immersion foot - Chilblain
Aerosinusitis - Hypoxia - Barotrauma - Altitude sickness - Chronic mountain sickness - Decompression sickness - Asphyxia - Starvation maltreatment (Physical abuse, Sexual abuse, Psychological abuse) Motion sickness (Airsickness, Sea-sickness) Electric shock - Anaphylaxis - Angioedema Hypersensitivity (Allergy, Arthus reaction) |
| Certain early complications of trauma | embolism (Air, Fat) - Crush syndrome/Rhabdomyolysis - Compartment syndrome/Volkmann's contracture |
| Complications of surgical and medical care | Serum sickness - Malignant hyperthermia |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
