Ankylosing spondylitis causes

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Ankylosing spondylitis Microchapters

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Differentiating Ankylosing spondylitis from other Diseases

Epidemiology and Demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Ankylosing spondylitis is an inflammatory disease that in overtime it causes some of the vertebrae in your spine to fuse.Because of the fusion the spine less flexible and the patients present with hunched-forward posture. It can be difficult to breathe deeply when the ribs are involved.The most common cause of ankylosing spondylitis is involvement of gene HLA B27.

Causes

Common Causes


References

  1. Reveille JD, Hirsch R, Dillon CF, Carroll MD, Weisman MH (May 2012). "The prevalence of HLA-B27 in the US: data from the US National Health and Nutrition Examination Survey, 2009". Arthritis Rheum. 64 (5): 1407–11. PMC 4038331Freely accessible. PMID 22139851. doi:10.1002/art.33503. 
  2. Reveille JD (July 2006). "The genetic basis of ankylosing spondylitis". Curr Opin Rheumatol. 18 (4): 332–41. PMID 16763451. doi:10.1097/01.bor.0000231899.81677.04. 
  3. Reveille JD, Weisman MH (June 2013). "The epidemiology of back pain, axial spondyloarthritis and HLA-B27 in the United States". Am. J. Med. Sci. 345 (6): 431–6. PMC 4122314Freely accessible. PMID 23841117. 
  4. Reveille JD (April 2011). "Epidemiology of spondyloarthritis in North America". Am. J. Med. Sci. 341 (4): 284–6. PMC 3063892Freely accessible. PMID 21430444. doi:10.1097/MAJ.0b013e31820f8c99. 

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