Acute myeloid leukemia chest x ray

Jump to: navigation, search

Acute myeloid leukemia Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Acute myeloid leukemia from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardigram

Chest X Ray

Echocardiograph and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Acute myeloid leukemia chest x ray On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Acute myeloid leukemia chest x ray

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Acute myeloid leukemia chest x ray

CDC on Acute myeloid leukemia chest x ray

Acute myeloid leukemia chest x ray in the news

Blogs on Acute myeloid leukemia chest x ray

Directions to Hospitals Treating Acute myeloid leukemia

Risk calculators and risk factors for Acute myeloid leukemia chest x ray

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2], Carlos A Lopez, M.D. [3], Shyam Patel [4]; Grammar Reviewer: Natalie Harpenau, B.S.[5]

Overview

Chest x-ray is useful for the diagnosis and evaluation of various aspects of acute myeloid leukemia management, including differentiation syndrome, infection, volume overload, and venous catheter placement.

Chest X-ray

The indications for chest X-ray in acute myeloid leukemia include assessment for the following:

  • Differentiation syndrome: Chest radiography is useful in the assessment of differentiation syndrome, which is a therapy-related complication when patients are treated with all-trans retinoic acid, enasidenib, or ivosidenib.[1] Chest X-ray will show pulmonary infiltrate and/or edema.[2]
  • Infection: Chest x-ray is routinely employed if a lung infection is suspected.[3] Bacterial, viral, and fungal pneumonias are very common in patients with acute myeloid leukemia receiving chemotherapy. Bacterial pneumonia will present as lobar consolidations on chest X-ray. Viral pneumonia will present as interstitial or reticular opacities on chest X-ray. Fungal pneumonia will present as nodules on chest X-ray.
  • Volume overload : Patients with acute myeloid leukemia typically received greater than 10 liters of intravenous fluids during induction chemotherapy. This can result in volume overload if diuresis is not appropriately administered. The accumulation of excess fluids within the pulmonary alveoli can result in pulmonary edema, which is readily detected on a chest X-ray as blunted costophrenic angles and Kerley B lines.
  • Venous catheter placement: Confirmation of the location of central access (central venous catheters) is done by obtaining a chest X-ray. Since patients with acute myeloid leukemia receive systemic chemotherapy, they usually have a peripherally-inserted central catheter or port, for which the catheter tip should terminate in the sinoatrial junction. A chest X-ray is needed to confirm placement.

References

  1. Cardinale L, Asteggiano F, Moretti F, Torre F, Ulisciani S, Fava C; et al. (2014). "Pathophysiology, clinical features and radiological findings of differentiation syndrome/all-trans-retinoic acid syndrome". World J Radiol. 6 (8): 583–8. doi:10.4329/wjr.v6.i8.583. PMC 4147438. PMID 25170395.
  2. Xu LM, Zheng YJ, Wang Y, Yang Y, Cao FF, Peng B; et al. (2014). "Celastrol inhibits lung infiltration in differential syndrome animal models by reducing TNF-α and ICAM-1 levels while preserving differentiation in ATRA-induced acute promyelocytic leukemia cells". PLoS One. 9 (8): e105131. doi:10.1371/journal.pone.0105131. PMC 4130635. PMID 25116125.
  3. Andronikou S, Lambert E, Halton J, Hilder L, Crumley I, Lyttle MD; et al. (2017). "Guidelines for the use of chest radiographs in community-acquired pneumonia in children and adolescents". Pediatr Radiol. 47 (11): 1405–1411. doi:10.1007/s00247-017-3944-4. PMC 5608836. PMID 29043422.

Linked-in.jpg