Tazobactam

Tazobactam

File:Tazobactam structure.svg
Clinical data
ATC code	J01CG02 (WHO)
Identifiers
IUPAC name (2S,3S,5R)-3-methyl-4,4,7-trioxo-3- (triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid
CAS Number	89786-04-9
DrugBank	EXPT03012
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C10H12N4O5S
Molar mass	300.289 g/mol

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Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin® or Zosyn®. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.

External links

• Zosyn (piperacillin / tazobactam)