Stress cardiomyopathy differential diagnosis: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
(11 intermediate revisions by 3 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Stress cardiomyopathy}}
{{Stress cardiomyopathy}}
{{CMG}}
{{CMG}}; {{AE}}{{DN}} {{AKK}}
==Overview==
==Overview==
The clinical presentation, laboratory findings and imaging studies of stress cardiomyopathy resembles that of [[anterior MI]] and must be differentiated from it. Also, stress cardiomyopathy must be differentiated from Takotsubo-like cardiomyopathy, such as that due to [[pheochromocytoma]].
== Differentiating Stress Cardiomyopathy from other Diseases ==
== Differentiating Stress Cardiomyopathy from other Diseases ==
The presentation of stress cardiomyopathy mimics that of [[Anterior myocardial infarction|anterior wall MI]] and must be differentiated from it:<ref name="pmid17223415">{{cite journal |vauthors=Parodi G, Del Pace S, Carrabba N, Salvadori C, Memisha G, Simonetti I, Antoniucci D, Gensini GF |title=Incidence, clinical findings, and outcome of women with left ventricular apical ballooning syndrome |journal=Am. J. Cardiol. |volume=99 |issue=2 |pages=182–5 |year=2007 |pmid=17223415 |doi=10.1016/j.amjcard.2006.07.080 |url=}}</ref>
The presentation of stress cardiomyopathy mimics that of [[Anterior myocardial infarction|anterior wall MI]] and must be differentiated from it. There are some studies in the literature comparing left ventricular functions between acute myocardial infarction and stress cardiomyopathy. Although, [[systolic]] functions of the [[left ventricle]] were more impaired in stress cardiomyopathy group compared with [[acute myocardial infarction]] group, [[diastolic]] functions were better in these patients. <ref name="pmid24503950">{{cite journal| author=Medeiros K, O'Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA et al.| title=Systolic and diastolic mechanics in stress cardiomyopathy. | journal=Circulation | year= 2014 | volume= 129 | issue= 16 | pages= 1659-67 | pmid=24503950 | doi=10.1161/CIRCULATIONAHA.113.002781 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24503950  }} </ref> <ref name="pmid19483168">{{cite journal| author=Park SM, Prasad A, Rihal C, Bell MR, Oh JK| title=Left ventricular systolic and diastolic function in patients with apical ballooning syndrome compared with patients with acute anterior ST-segment elevation myocardial infarction: a functional paradox. | journal=Mayo Clin Proc | year= 2009 | volume= 84 | issue= 6 | pages= 514-21 | pmid=19483168 | doi=10.1016/S0025-6196(11)60583-1 | pmc=2688625 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19483168  }} </ref>
 
{| class="wikitable"
{| class="wikitable"
!
!Disease
!Stress Cardiomyopathy
!Can Present With
!Anterior Wall MI
!Cardiac Enzymes
!Catecholamine Levels
!ECG Findings
!Echocardiography Findings
|-
|-
|[[Chest pain]] and [[dyspnea]] as presenting symptoms
|Stress Cardiomyopathy
|
|[[Chest pain]], [[dyspnea]]
|
|
|Transiently elevated
|[[ST elevation]] in [[precordial leads]]
|[[LV]] regional dysfunction
|-
|-
|[[Pheochromocytoma]]
|[[Chest pain]], [[dyspnea]]
|Can be positive
|Persistently elevated
|[[ST elevation]] in [[precordial leads]]
|[[ST elevation]] in [[precordial leads]]
|
|[[LV]] regional dysfunction
|✔
|-
|-
|Peak [[CK-MB]] value
|[[Anterior MI]]
|<50 U/L
|[[Chest pain]], [[dyspnea]]
|↑↑↑
|↑↑↑
| -
|[[ST elevation]] in [[precordial leads]]
|Dysfunction at area of [[infarction]]
|-
|-
|6-month outcome
|[[Myocarditis]]
|Favorable outcome
|[[Chest pain]], [[dyspnea]], [[fever]]
|Higher rates of:
|May be acutely elevated
* Death
| -
* Cardiac death
|May show [[atrial fibrillation]], [[Left bundle branch block|LBBB]] or [[AV block]]
* [[Reinfarction]]
|Diffuse [[hypokinesia]]
* Rehospitalization
* Major cardiac events
|}
Stress cardiomyopathy must also be differentiated from Takotsobu-like syndrome, caused by medical conditions, such as [[pheochromocytoma]]:
{| class="wikitable"
!
!Stress Cardiomyopathy
!Takotsobu-like Syndrome
|-
|[[Chest pain]] mimicking [[MI]]
|
|✔
|-
|[[EKG]] findings ([[ST elevation]])
|✔
|✔
|-
|Positive [[cardiac enzymes]]
|
|✔
|-
|[[LV]] regional dysfunction
|✔
|✔
|-
|Patient profile
|Post-menopausal women
|Younger patients with less female predominance
|-
|-
|[[Catecholamine]] levels
|[[Dilated cardiomyopathy|Dilated Cardiomyopathy]]
|Transient elevation
|[[Dyspnea]], [[dyspnea on exertion]], [[cough]], [[edema]], [[fatigue]]
|Constantly elevated
|Usually negative
| -
|May show [[atrial fibrillation]], [[Left bundle branch block|LBBB]] or [[AV block]]
|[[LV]] enlargement
|-
|-
|Complications
|[[Hypertrophic Cardiomyopathy]]
|
|[[Chest pain]], [[dyspnea]], [[syncope]], [[sudden cardiac death]]
|Higher rate of complications, including:
|Usually negative
* [[Cardiogenic shock]]
| -
* [[Heart failure]]
|Common findings include:
* Low [[Ejection fraction|ejection fraction (EF)]]
* [[Right axis deviation|Right]] or [[left axis deviation]]
* [[Bundle branch block|BBB]]
* [[Sinus bradycardia]]
|[[LV hypertrophy]], [[systolic]] anterior motion of the [[mitral valve]], asymmetric septal [[hypertrophy]]
|}
|}



Latest revision as of 18:55, 1 February 2019

Stress cardiomyopathy Microchapters

Home

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Stress Cardiomyopathy from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Unstable angina/non ST elevation myocardial infarction in Stress (Takotsubo) Cardiomyopathy

Future or Investigational Therapies

Case Studies

Case #1

Stress cardiomyopathy differential diagnosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Stress cardiomyopathy differential diagnosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Stress cardiomyopathy differential diagnosis

CDC on Stress cardiomyopathy differential diagnosis

Stress cardiomyopathy differential diagnosis in the news

Blogs on Stress cardiomyopathy differential diagnosis

Directions to Hospitals Treating Stress cardiomyopathy

Risk calculators and risk factors for Stress cardiomyopathy differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2] Arzu Kalayci, M.D. [3]

Overview

The clinical presentation, laboratory findings and imaging studies of stress cardiomyopathy resembles that of anterior MI and must be differentiated from it. Also, stress cardiomyopathy must be differentiated from Takotsubo-like cardiomyopathy, such as that due to pheochromocytoma.

Differentiating Stress Cardiomyopathy from other Diseases

The presentation of stress cardiomyopathy mimics that of anterior wall MI and must be differentiated from it. There are some studies in the literature comparing left ventricular functions between acute myocardial infarction and stress cardiomyopathy. Although, systolic functions of the left ventricle were more impaired in stress cardiomyopathy group compared with acute myocardial infarction group, diastolic functions were better in these patients. [1] [2]

Disease Can Present With Cardiac Enzymes Catecholamine Levels ECG Findings Echocardiography Findings
Stress Cardiomyopathy Chest pain, dyspnea Transiently elevated ST elevation in precordial leads LV regional dysfunction
Pheochromocytoma Chest pain, dyspnea Can be positive Persistently elevated ST elevation in precordial leads LV regional dysfunction
Anterior MI Chest pain, dyspnea ↑↑↑ - ST elevation in precordial leads Dysfunction at area of infarction
Myocarditis Chest pain, dyspnea, fever May be acutely elevated - May show atrial fibrillation, LBBB or AV block Diffuse hypokinesia
Dilated Cardiomyopathy Dyspnea, dyspnea on exertion, cough, edema, fatigue Usually negative - May show atrial fibrillation, LBBB or AV block LV enlargement
Hypertrophic Cardiomyopathy Chest pain, dyspnea, syncope, sudden cardiac death Usually negative - Common findings include: LV hypertrophy, systolic anterior motion of the mitral valve, asymmetric septal hypertrophy

References

  1. Medeiros K, O'Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA; et al. (2014). "Systolic and diastolic mechanics in stress cardiomyopathy". Circulation. 129 (16): 1659–67. doi:10.1161/CIRCULATIONAHA.113.002781. PMID 24503950.
  2. Park SM, Prasad A, Rihal C, Bell MR, Oh JK (2009). "Left ventricular systolic and diastolic function in patients with apical ballooning syndrome compared with patients with acute anterior ST-segment elevation myocardial infarction: a functional paradox". Mayo Clin Proc. 84 (6): 514–21. doi:10.1016/S0025-6196(11)60583-1. PMC 2688625. PMID 19483168.

Template:WH Template:WS