Scleroderma history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The hallmark of scleroderma is sclerodactyly. A positive history of progressive skin tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include skin tightening or induration, | The hallmark of scleroderma is [[sclerodactyly]]. A positive history of progressive [[skin]] tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include [[skin]] tightening or [[induration]], [[Raynaud's phenomenon]], and symptoms of [[gastroesophageal reflux disease]] (GERD). Less common symptoms of scleroderma include shiny [[skin]] appearance and restricted movement of affected areas of the [[skin]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
The hallmark of scleroderma is sclerodactyly. A positive history of progressive skin tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include skin tightening or induration, | The hallmark of scleroderma is [[sclerodactyly]]. A positive history of progressive [[skin]] tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include [[skin]] tightening or [[induration]], [[Raynaud's phenomenon]] and symptoms of [[gastroesophageal reflux disease]] (GERD).<ref name="pmid28133631">{{cite journal |vauthors=Shreiner AB, Murray C, Denton C, Khanna D |title=Gastrointestinal Manifestations of Systemic Sclerosis |journal=J Scleroderma Relat Disord |volume=1 |issue=3 |pages=247–256 |date=2016 |pmid=28133631 |pmc=5267349 |doi=10.5301/jsrd.5000214 |url=}}</ref> | ||
===History=== | ===History=== | ||
Patients with scleroderma may have a positive history of: | Patients with scleroderma may have a positive history of: | ||
*Progressive skin tightening or hardening | *Progressive [[skin]] tightening or hardening<ref name="pmid17017489">{{cite journal |vauthors=Pogorzelska-Antkowiak A, Antkowiak R |title=[Diagnostic and therapeutic problems of scleroderma] |language=Polish |journal=Wiad. Lek. |volume=59 |issue=5-6 |pages=392–5 |date=2006 |pmid=17017489 |doi= |url=}}</ref><ref name="pmid20453602">{{cite journal |vauthors=Hudson M, Fritzler MJ, Baron M |title=Systemic sclerosis: establishing diagnostic criteria |journal=Medicine (Baltimore) |volume=89 |issue=3 |pages=159–65 |date=May 2010 |pmid=20453602 |doi=10.1097/MD.0b013e3181dde28d |url=}}</ref> | ||
*Skin induration affecting fingers and extending proximally (sclerodactyly) | *Skin [[induration]] affecting fingers and extending proximally ([[sclerodactyly]])<ref name="pmid17017489">{{cite journal |vauthors=Pogorzelska-Antkowiak A, Antkowiak R |title=[Diagnostic and therapeutic problems of scleroderma] |language=Polish |journal=Wiad. Lek. |volume=59 |issue=5-6 |pages=392–5 |date=2006 |pmid=17017489 |doi= |url=}}</ref><ref name="pmid20453602">{{cite journal |vauthors=Hudson M, Fritzler MJ, Baron M |title=Systemic sclerosis: establishing diagnostic criteria |journal=Medicine (Baltimore) |volume=89 |issue=3 |pages=159–65 |date=May 2010 |pmid=20453602 |doi=10.1097/MD.0b013e3181dde28d |url=}}</ref> | ||
*Exaggerated response to cold temperatures or emotional stress causing numbness, pain or color changes in fingers or toes (Raynaud's | *Exaggerated response to cold temperatures or emotional stress causing [[numbness]], [[pain]] or color changes in fingers or toes ([[Raynaud's phenomenon]])<ref name="pmid20453602">{{cite journal |vauthors=Hudson M, Fritzler MJ, Baron M |title=Systemic sclerosis: establishing diagnostic criteria |journal=Medicine (Baltimore) |volume=89 |issue=3 |pages=159–65 |date=May 2010 |pmid=20453602 |doi=10.1097/MD.0b013e3181dde28d |url=}}</ref> | ||
*Swallowing difficulty | *[[Swallowing difficulty]]<ref name="pmid28133631">{{cite journal |vauthors=Shreiner AB, Murray C, Denton C, Khanna D |title=Gastrointestinal Manifestations of Systemic Sclerosis |journal=J Scleroderma Relat Disord |volume=1 |issue=3 |pages=247–256 |date=2016 |pmid=28133631 |pmc=5267349 |doi=10.5301/jsrd.5000214 |url=}}</ref> | ||
*Bloating | *[[Heartburn]] | ||
*Flatulence | *[[Abdominal pain]] | ||
*Altered bowel movements | *[[Nausea]] | ||
*Fatigue | *[[Vomiting]] | ||
*Weakness | *[[Bloating]] | ||
*Weight loss | *[[Flatulence]] | ||
*Musculoskeletal pain | *Altered [[Bowel movement|bowel movements]] | ||
*[[Fatigue]]<ref name="pmid19106163">{{cite journal |vauthors=Sandusky SB, McGuire L, Smith MT, Wigley FM, Haythornthwaite JA |title=Fatigue: an overlooked determinant of physical function in scleroderma |journal=Rheumatology (Oxford) |volume=48 |issue=2 |pages=165–9 |date=February 2009 |pmid=19106163 |pmc=2638541 |doi=10.1093/rheumatology/ken455 |url=}}</ref> | |||
*[[Weakness]] | |||
*[[Weight loss]] | |||
*[[Musculoskeletal pain]] | |||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of scleroderma include: | Common symptoms of scleroderma include: | ||
*Skin tightening and induration (hardening) | *[[Skin]] tightening and [[induration]] (hardening)<ref name="pmid17017489">{{cite journal |vauthors=Pogorzelska-Antkowiak A, Antkowiak R |title=[Diagnostic and therapeutic problems of scleroderma] |language=Polish |journal=Wiad. Lek. |volume=59 |issue=5-6 |pages=392–5 |date=2006 |pmid=17017489 |doi= |url=}}</ref><ref name="pmid20453602">{{cite journal |vauthors=Hudson M, Fritzler MJ, Baron M |title=Systemic sclerosis: establishing diagnostic criteria |journal=Medicine (Baltimore) |volume=89 |issue=3 |pages=159–65 |date=May 2010 |pmid=20453602 |doi=10.1097/MD.0b013e3181dde28d |url=}}</ref> | ||
*Exaggerated response to cold temperatures or emotional stress causing numbness, pain or color changes in fingers or toes (Raynaud's Phenomenon) | *Exaggerated response to cold temperatures or emotional stress causing [[numbness]], [[pain]] or color changes in fingers or toes ([[Raynaud's phenomenon|Raynaud's Phenomenon]])<ref name="pmid20453602">{{cite journal |vauthors=Hudson M, Fritzler MJ, Baron M |title=Systemic sclerosis: establishing diagnostic criteria |journal=Medicine (Baltimore) |volume=89 |issue=3 |pages=159–65 |date=May 2010 |pmid=20453602 |doi=10.1097/MD.0b013e3181dde28d |url=}}</ref> | ||
*Non-productive cough | *Non-productive [[cough]]<ref name="pmid20453602">{{cite journal |vauthors=Hudson M, Fritzler MJ, Baron M |title=Systemic sclerosis: establishing diagnostic criteria |journal=Medicine (Baltimore) |volume=89 |issue=3 |pages=159–65 |date=May 2010 |pmid=20453602 |doi=10.1097/MD.0b013e3181dde28d |url=}}</ref> | ||
*Chest tightness | *[[Chest]] tightness | ||
*Chest pain | *[[Chest pain]] | ||
*Joint pain | *[[Joint pain]] | ||
*[[Dysphagia]]<ref name="pmid28133631">{{cite journal |vauthors=Shreiner AB, Murray C, Denton C, Khanna D |title=Gastrointestinal Manifestations of Systemic Sclerosis |journal=J Scleroderma Relat Disord |volume=1 |issue=3 |pages=247–256 |date=2016 |pmid=28133631 |pmc=5267349 |doi=10.5301/jsrd.5000214 |url=}}</ref><ref name="pmid20453602">{{cite journal |vauthors=Hudson M, Fritzler MJ, Baron M |title=Systemic sclerosis: establishing diagnostic criteria |journal=Medicine (Baltimore) |volume=89 |issue=3 |pages=159–65 |date=May 2010 |pmid=20453602 |doi=10.1097/MD.0b013e3181dde28d |url=}}</ref> | |||
*[[Abdominal pain]] | |||
*[[Diarrhea]] | |||
*[[Constipation]] | |||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of scleroderma include: | Less common symptoms of scleroderma include: | ||
*Shiny skin appearance | *Shiny [[skin]] appearance | ||
*Restricted movement of affected area of skin | *Restricted movement of affected area of [[skin]] | ||
==References== | ==References== | ||
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[[Category:Dermatology]] | |||
[[Category:Rheumatology]] | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
The hallmark of scleroderma is sclerodactyly. A positive history of progressive skin tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include skin tightening or induration, Raynaud's phenomenon, and symptoms of gastroesophageal reflux disease (GERD). Less common symptoms of scleroderma include shiny skin appearance and restricted movement of affected areas of the skin.
History and Symptoms
The hallmark of scleroderma is sclerodactyly. A positive history of progressive skin tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include skin tightening or induration, Raynaud's phenomenon and symptoms of gastroesophageal reflux disease (GERD).[1]
History
Patients with scleroderma may have a positive history of:
- Progressive skin tightening or hardening[2][3]
- Skin induration affecting fingers and extending proximally (sclerodactyly)[2][3]
- Exaggerated response to cold temperatures or emotional stress causing numbness, pain or color changes in fingers or toes (Raynaud's phenomenon)[3]
- Swallowing difficulty[1]
- Heartburn
- Abdominal pain
- Nausea
- Vomiting
- Bloating
- Flatulence
- Altered bowel movements
- Fatigue[4]
- Weakness
- Weight loss
- Musculoskeletal pain
Common Symptoms
Common symptoms of scleroderma include:
- Skin tightening and induration (hardening)[2][3]
- Exaggerated response to cold temperatures or emotional stress causing numbness, pain or color changes in fingers or toes (Raynaud's Phenomenon)[3]
- Non-productive cough[3]
- Chest tightness
- Chest pain
- Joint pain
- Dysphagia[1][3]
- Abdominal pain
- Diarrhea
- Constipation
Less Common Symptoms
Less common symptoms of scleroderma include:
References
- ↑ 1.0 1.1 1.2 Shreiner AB, Murray C, Denton C, Khanna D (2016). "Gastrointestinal Manifestations of Systemic Sclerosis". J Scleroderma Relat Disord. 1 (3): 247–256. doi:10.5301/jsrd.5000214. PMC 5267349. PMID 28133631.
- ↑ 2.0 2.1 2.2 Pogorzelska-Antkowiak A, Antkowiak R (2006). "[Diagnostic and therapeutic problems of scleroderma]". Wiad. Lek. (in Polish). 59 (5–6): 392–5. PMID 17017489.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Hudson M, Fritzler MJ, Baron M (May 2010). "Systemic sclerosis: establishing diagnostic criteria". Medicine (Baltimore). 89 (3): 159–65. doi:10.1097/MD.0b013e3181dde28d. PMID 20453602.
- ↑ Sandusky SB, McGuire L, Smith MT, Wigley FM, Haythornthwaite JA (February 2009). "Fatigue: an overlooked determinant of physical function in scleroderma". Rheumatology (Oxford). 48 (2): 165–9. doi:10.1093/rheumatology/ken455. PMC 2638541. PMID 19106163.