Scleroderma historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]

Overview

The word scleroderma comes from greek words; skleros (hard) and derma (skin). Scleroderma was first described by Carlo Curzio in Naples, Italy in 1753. The association between abnormal vasoconstriction and diffuse scleroderma was made in 1865 by Raynaud.

Historical Perspective

Discovery

  • The word scleroderma comes from greek words; skleros (hard) and derma (skin).[1]
  • Hippocrates, in his literature has also described scleroderma as a patient having hard skin.[2]
  • Scleroderma was first described by Carlo Curzio in Naples, Italy in 1753.[3]
  • The term scleroderma was first used by Fantonetti in 1837.
  • The association between abnormal vasoconstriction and diffuse scleroderma was made in 1865 by Raynaud.

References

  1. Boin F, Hummers LK (February 2008). "Scleroderma-like fibrosing disorders". Rheum. Dis. Clin. North Am. 34 (1): 199–220, ix. doi:10.1016/j.rdc.2007.11.001. PMC 2706095. PMID 18329541.
  2. Morgan ND, Hummers LK (March 2016). "Scleroderma Mimickers". Curr Treatm Opt Rheumatol. 2 (1): 69–84. doi:10.1007/s40674-016-0038-7. PMC 5412724. PMID 28473954.
  3. RODNAN GP, BENEDEK TG (August 1962). "An historical account of the study of progressive systemic sclerosis (diffuse scleroderma)". Ann. Intern. Med. 57: 305–19. PMID 14493141.

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