SNTG1: Difference between revisions
Jump to navigation
Jump to search
m (Bot: HTTP→HTTPS) |
m (added wikilinks and removed "underlinked" tag) |
||
| Line 1: | Line 1: | ||
{{Infobox_gene}} | {{Infobox_gene}} | ||
'''Gamma-1-syntrophin''' is a [[protein]] that in humans is encoded by the ''SNTG1'' [[gene]].<ref name="pmid10747910">{{cite journal | vauthors = Piluso G, Mirabella M, Ricci E, Belsito A, Abbondanza C, Servidei S, Puca AA, Tonali P, Puca GA, Nigro V | title = Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells | journal = J Biol Chem | volume = 275 | issue = 21 | pages = 15851–60 |date=Jun 2000 | pmid = 10747910 | pmc = | doi = 10.1074/jbc.M000439200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNTG1 syntrophin, gamma 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54212| accessdate = }}</ref> | '''Gamma-1-syntrophin''' is a [[protein]] that in humans is encoded by the ''SNTG1'' [[gene]].<ref name="pmid10747910">{{cite journal | vauthors = Piluso G, Mirabella M, Ricci E, Belsito A, Abbondanza C, Servidei S, Puca AA, Tonali P, Puca GA, Nigro V | title = Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells | journal = J Biol Chem | volume = 275 | issue = 21 | pages = 15851–60 |date=Jun 2000 | pmid = 10747910 | pmc = | doi = 10.1074/jbc.M000439200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNTG1 syntrophin, gamma 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54212| accessdate = }}</ref> | ||
| Line 6: | Line 6: | ||
{{PBB_Summary | {{PBB_Summary | ||
| section_title = | | section_title = | ||
| summary_text = The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain. Transcript variants for this gene have been described, but their full-length nature has not been determined.<ref name="entrez" /> | | summary_text = The protein encoded by this gene is a member of the [[syntrophin]] family. Syntrophins are cytoplasmic [[peripheral membrane proteins]] that typically contain 2 [[pleckstrin homology]] (PH) domains, a [[PDZ domain]] that bisects the first PH domain, and a C-terminal domain that mediates [[dystrophin]] binding. This gene is specifically expressed in the [[brain]]. [[Transcript variants]] for this gene have been described, but their full-length nature has not been determined.<ref name="entrez" /> | ||
}} | }} | ||
Revision as of 19:31, 20 February 2018
| VALUE_ERROR (nil) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Aliases | |||||||
| External IDs | GeneCards: [1] | ||||||
| Orthologs | |||||||
| Species | Human | Mouse | |||||
| Entrez |
|
| |||||
| Ensembl |
|
| |||||
| UniProt |
|
| |||||
| RefSeq (mRNA) |
|
| |||||
| RefSeq (protein) |
|
| |||||
| Location (UCSC) | n/a | n/a | |||||
| PubMed search | n/a | n/a | |||||
| Wikidata | |||||||
| |||||||
Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene.[1][2]
The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain. Transcript variants for this gene have been described, but their full-length nature has not been determined.[2]
References
- ↑ Piluso G, Mirabella M, Ricci E, Belsito A, Abbondanza C, Servidei S, Puca AA, Tonali P, Puca GA, Nigro V (Jun 2000). "Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells". J Biol Chem. 275 (21): 15851–60. doi:10.1074/jbc.M000439200. PMID 10747910.
- ↑ 2.0 2.1 "Entrez Gene: SNTG1 syntrophin, gamma 1".
Further reading
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Hogan A, Shepherd L, Chabot J, et al. (2001). "Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions". J. Biol. Chem. 276 (28): 26526–33. doi:10.1074/jbc.M104156200. PMID 11352924.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Widberg CH, Bryant NJ, Girotti M, et al. (2003). "Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation". J. Biol. Chem. 278 (37): 35093–101. doi:10.1074/jbc.M304261200. PMID 12832401.
- Buxton P, Zhang XM, Walsh B, et al. (2004). "Identification and characterization of Snapin as a ubiquitously expressed SNARE-binding protein that interacts with SNAP23 in non-neuronal cells". Biochem. J. 375 (Pt 2): 433–40. doi:10.1042/BJ20030427. PMC 1223698. PMID 12877659.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Chen Z, Hague C, Hall RA, Minneman KP (2006). "Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction". J. Biol. Chem. 281 (18): 12414–20. doi:10.1074/jbc.M508651200. PMID 16533813.
 | This article on a gene on human chromosome 8 is a stub. You can help Wikipedia by expanding it. |