Non-alcoholic fatty liver disease causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

Oxidative stress, hormonal imbalances, endotoxemia and mitochondrial abnormalities may all be potential causes. It can be caused by some medications, and it is referred to as secondary NAFLD.

Causes

• Common causes in the development of NAFLD is related to obesity which will result in insulin resistance and metabolic syndrome.It is estimated that approximately 80% of the obese people suffer from NAFLD.
• Patients who are having type 2 diabetes mellitus are more prone to develop Nafld

• Less commonly Patients with hypertension and dyslipidemia are also associated with developing NAFLD

Secondary causes

NAFLD can also be caused by the following medications (termed secondary NAFLD):

• Amiodarone
• Antiviral drugs (nucleoside analogues)
• Aspirin / NSAIDS
• Corticosteroids
• Methotrexate
• Nifedipine
• Perhexiline
• Tamoxifen
• Tetracycline
• Valproic acid
• Viral Hepatitis.
• Rapid weight loss.
• Malnutrition.
• High levels of triglyceride in blood.
• Sleep apnea.
• Hypothyroidism
• Hypopituitarism .

References

Non-Alcoholic Fatty Liver Disease Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Non-Alcoholic Fatty Liver Disease from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case studies
Case #1
Non-alcoholic fatty liver disease causes On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Non-alcoholic fatty liver disease causes All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Non-alcoholic fatty liver disease causes
CDC on Non-alcoholic fatty liver disease causes
Non-alcoholic fatty liver disease causes in the news
Blogs on Non-alcoholic fatty liver disease causes
Directions to Hospitals Treating Non-alcoholic fatty liver disease
Risk calculators and risk factors for Non-alcoholic fatty liver disease causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-in-Chief:

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