Multiple endocrine neoplasia type 2 other imaging findings

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Multiple endocrine neoplasia type 2 Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Other Imaging Studies

Medullary Thyroid Carcinoma

  • Radioactive iodine: lesions do not concentrate radioactive iodine since the tumour does not arise from thyroid follicular cells.
  • FDG-PET: avid uptake
  • Tl-201: It has been shown to concentrate Thallium-201[1]
  • I-123 MIBG: 30% of MTCs show uptake if the thyroid is blocked with Lugol solution prior to the scan

Pheochromocytoma

  • [18F]-fluorodopamine ([18F]DA) PET is the best imaging modality for pheochromocytoma
  • MIBG (123I- or 131I- metaiodobenzylguanidine) scintigraphy is another imaging modality for pheochromocytoma

Parahyroid Carcinoma

  • 99mTc-sestamibi scintigraphy is a good imaging modality for hyperparathyroidism.

Reference

  1. Talpos GB, Jackson CE, Froelich JW, Kambouris AA, Block MA, Tashjian AH (1985). "Localization of residual medullary thyroid cancer by thallium/technetium scintigraphy". Surgery. 98 (6): 1189–96. PMID 2866591.
  2. "http://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="http://radiopaedia.org/cases/7932">rID: 7932
  3. "http://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="http://radiopaedia.org/cases/16148">rID: 16148