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{{Mitral valve prolapse}}
{{Mitral valve prolapse}}
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}
==Mitral valve prolapse syndrome==
'''Mitral valve prolapse syndrome''' ('''MVP Syndrome'''), also referred to as '''mitral valve prolapse dysautonomia''', is thought to represent an imbalance of the [[autonomic nervous system]] in association with mitral valve prolapse.  The underlying etiology that causes both autonomic dysregulation and the structural abnormalities present in mitral valve prolapse is unknown.  Most patients who suffer from mitral valve prolapse syndrome may have an underlying [[dysautonomia]] as the cause of their symptoms.  In particular, supraventricular arrhythmias such as those observed with MVP syndrome are associated with increased parasympathetic tone.<ref name="Terechtchenko-2003">{{cite journal | author=Terechtchenko L, Doronina SA, Pochinok EM, Riftine A. | title=Autonomic tone in patients with supraventricular arrhythmia associated with mitral valve prolapse in young men. | journal=Pacing Clin Electrophysiol | year=2003 | volume=26 | issue=1 Pt 2 | pages=444-6 | pmid=12687863}}</ref>
Symptoms generally attributed to MVP syndrome include [[palpitations]], [[shortness of breath]], and [[fainting|syncope]].  Because of the low specificity of these symptoms, and the fact that there is significant overlap in the causes of these symptoms with sequelae of significant [[mitral regurgitation]] often seen with mitral valve prolapse, MVP syndrome is most likely over-diagnosed.<ref name=Fogoros>{{cite web
  | last = Fogoros
  | first = Richard N.
  | title = Mitral Valve Prolapse (MVP)
  | url=http://heartdisease.about.com/library/weekly/aa073100b.htm
  | work=Heart Disease
  | publisher=About.com
  | accessdate = 2007-07-11}}</ref>  The uncertainty regarding the frequency of this syndrome may in part be due to the fact that there is no consensus criteria to diagnose MVP syndrome.


== [[Mitral valve prolapse overview|Overview]] ==
== [[Mitral valve prolapse overview|Overview]] ==
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[[Mitral valve prolapse medical therapy|Medical Therapy]] | [[Mitral valve prolapse surgery|Surgery]] | [[Mitral valve prolapse primary prevention|Primary Prevention]] | [[Mitral valve prolapse secondary prevention|Secondary Prevention]] | [[Mitral valve prolapse cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Mitral valve prolapse future or investigational therapies|Future or Investigational Therapies]]
[[Mitral valve prolapse medical therapy|Medical Therapy]] | [[Mitral valve prolapse surgery|Surgery]] | [[Mitral valve prolapse primary prevention|Primary Prevention]] | [[Mitral valve prolapse secondary prevention|Secondary Prevention]] | [[Mitral valve prolapse cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Mitral valve prolapse future or investigational therapies|Future or Investigational Therapies]]
== References ==
{{Reflist|2}}


== External links ==
== External links ==

Revision as of 14:27, 21 August 2012

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Mitral valve prolapse
Mitral Valve Prolapse: Gross natural color view from left atrium showing prolapsed anterior leaflet into atrium Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology
ICD-10 I34.1
ICD-9 394.0, 424.0
OMIM 157700
DiseasesDB 8303
MedlinePlus 000180
MeSH D008945

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

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