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==Overview==
==Overview==
The [[prevalence]] of [[menopause]] is estimated to be about 50 million cases annually. [[Menopause]] naturally occurs in [[women]] between 49 to 52 of [[age]] the [[average]]. The [[Fatality rate|fatality]] cases were 345 cases per 3191 [[women]] aged between 50-86 years in the [[United States]]. There is no [[racial]] predilection to [[Menopause]],  but  African American [[women]] had experienced the largest number of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] compared with other [[Ethnic group|ethnic groups]].


*In1990, there were 467 million [[menopausal]] [[women]] worldwide. The prevalence of [[menopause]] is estimated to be about 25 million cases annually. By 2030, the number of [[menopausal]] [[women]] is projected to increase to 1.2 billion worldwide, with 47 million new cases annually
==Epidemiology and Demographics==
===Prevalence and Incidence===
 
*The [[prevalence]] of [[menopause]] is estimated to be about 50 million cases worldwide will go into [[menopause]] annually.<ref name="pmid11716989">{{cite journal| author=Massart F, Reginster JY, Brandi ML| title=Genetics of menopause-associated diseases. | journal=Maturitas | year= 2001 | volume= 40 | issue= 2 | pages= 103-16 | pmid=11716989 | doi=10.1016/s0378-5122(01)00283-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11716989  }} </ref>
 
*In 1990 there were 467 million [[postmenopausal]] women in the world, by 2030, [[menopausal]] [[women]] are projected to increase to 1.2 billion worldwide.<ref name="pmid8735350">{{cite journal| author=Hill K| title=The demography of menopause. | journal=Maturitas | year= 1996 | volume= 23 | issue= 2 | pages= 113-27 | pmid=8735350 | doi=10.1016/0378-5122(95)00968-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8735350  }} </ref>
*The [[prevalence]] of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] differ in [[women]] according to areas and countries that they live them, the [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms]  ranges from 74% of [[women]] in Europe, 36-50% in North America, 45-69% in [[Latin America]] and 22-63% in Asia.<ref name="pmid20690868">{{cite journal| author=Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P| title=Age of menopause and impact of climacteric symptoms by geographical region. | journal=Climacteric | year= 2010 | volume= 13 | issue= 5 | pages= 419-28 | pmid=20690868 | doi=10.3109/13697137.2010.507886 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20690868  }} </ref>
*The [[prevalence]] of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] among [[women]] prescribed [[hormone therapy]] ([[Hormonal therapy|HT]]), the mean age of patients was 54 years. The most common [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] were: [[hot flushes]] (40 %), [[night sweats]] (17 %), [[insomnia]] (16 %), [[vaginal dryness]] (13 %), [[mood disorders]] (12 %), and [[weight gain]] (12 %).
*85 % of [[postmenopausal]] [[women]] have experienced a [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptom] in their lifetime, and the prevalence of [https://www.contemporaryobgyn.net/view/managing-menopause-part-1-vasomotor-symptoms vasomotor symptoms]( [[hot flushes]] and/or [[night sweats]]) alone is estimated at approximately 40 to 50 million [[women]] in the [[United States]].<ref name="pmid26271251">{{cite journal| author=Sussman M, Trocio J, Best C, Mirkin S, Bushmakin AG, Yood R | display-authors=etal| title=Prevalence of menopausal symptoms among mid-life women: findings from electronic medical records. | journal=BMC Womens Health | year= 2015 | volume= 15 | issue=  | pages= 58 | pmid=26271251 | doi=10.1186/s12905-015-0217-y | pmc=4542113 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26271251  }} </ref>


==Epidemiology and Demographics==
<br />
===Age===


====Prevalence and Incidence====
*The onset [[age]] of [[menopause]] between the [[Age|ages]] of 50-53 in Europe.
*In 1990 there were 467 million postmenopausal women in the world, with an average age of about 60 years, and the prevalence of menopause is estimated to be about 25 million cases worldwide will go into menopause annually.  
*In North America, the onset [[age]] of [[menopause]] from 50-51years.
*By 2030, menopausal women are projected to increase to 1.2 billion worldwide, with 47 million new cases annually.<ref name="pmid8735350">{{cite journal| author=Hill K| title=The demography of menopause. | journal=Maturitas | year= 1996 | volume= 23 | issue= 2 | pages= 113-27 | pmid=8735350 | doi=10.1016/0378-5122(95)00968-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8735350  }} </ref>
*In [[Latin America]], the onset [[age]] of [[menopause]] from 44- 53 years.
* The prevalence of menopausal symptoms differ in women according to areas and countries that they live them, the menopausal symptoms  ranges from 74% of women in Europe, 36-50% in North America, 45-69% in Latin America and 22-63% in Asia.<ref name="pmid20690868">{{cite journal| author=Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P| title=Age of menopause and impact of climacteric symptoms by geographical region. | journal=Climacteric | year= 2010 | volume= 13 | issue= 5 | pages= 419-28 | pmid=20690868 | doi=10.3109/13697137.2010.507886 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20690868 }} </ref>
*In Asia, the onset [[age]] of [[menopause]] from 42-49 years.<ref name="pmid20690868">{{cite journal| author=Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P| title=Age of menopause and impact of climacteric symptoms by geographical region. | journal=Climacteric | year= 2010 | volume= 13 | issue= 5 | pages= 419-28 | pmid=20690868 | doi=10.3109/13697137.2010.507886 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20690868  }} </ref>
*The prevalence of menopausal symptoms among women prescribed hormone therapy (HT), the mean age of patients was 54 years. The most common menopausal symptoms were: hot flushes (40 %), night sweats (17 %), insomnia (16 %), vaginal dryness (13 %), mood disorders (12 %), and weight gain (12 %). Among the 102 patients, 163 individual visits listing menopausal symptoms were identified, of which hot flushes (71 visits) were the most common symptom identified. 85 % of postmenopausal women have experienced a menopause-related symptom in their lifetime, and the Prevalence of vasomotor symptoms( hot flushes and/or night sweats) alone is estimated at approximately 40 to 50 million women in the United States.<ref name="pmid26271251">{{cite journal| author=Sussman M, Trocio J, Best C, Mirkin S, Bushmakin AG, Yood R | display-authors=etal| title=Prevalence of menopausal symptoms among mid-life women: findings from electronic medical records. | journal=BMC Womens Health | year= 2015 | volume= 15 | issue=  | pages= 58 | pmid=26271251 | doi=10.1186/s12905-015-0217-y | pmc=4542113 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26271251  }} </ref>
*[https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 Menopausal symptoms] differ in women according to areas and countries that they live them e.g. [[shoulder pain]] in Japan, [[hot flush]] In the West, and low [[vision]] in India.<ref name="pmid15981376">{{cite journal| author=Singh A, Kaur S, Walia I| title=A historical perspective on menopause and menopausal age. | journal=Bull Indian Inst Hist Med Hyderabad | year= 2002 | volume= 32 | issue= 2 | pages= 121-35 | pmid=15981376 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15981376 }} </ref>


====Age====
===Mortality rate===
*The onset age of menopause between the ages of 50-53 in Europe.
*In North America, the onset age of menopause from 50-51years.
*In Latin America, the onset age of menopause from 44- 53 years.
*In Asia, the onset age of menopause from 42-49 years.<ref name="pmid20690868">{{cite journal| author=Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P| title=Age of menopause and impact of climacteric symptoms by geographical region. | journal=Climacteric | year= 2010 | volume= 13 | issue= 5 | pages= 419-28 | pmid=20690868 | doi=10.3109/13697137.2010.507886 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20690868  }} </ref>


====Mortality rate====
*In 1997, the [[Fatality rate|fatality]] cases were 345 cases per 3191 [[women]] aged between 50-86 years in the [[United States]] over a mean follow-up time of 4.0 years.
*In 1997, the fatality cases were 345 cases per 3191 women aged between 50-86 years in the United States over a mean follow-up time of 4.0 years.
*The [[Mortality ratio|mortality rate ratio]] ([[Mortality ratio|MRR]]) was 1.50% for [[women]] with [[menopause]] at [[age]] < 40, and the [[Mortality ratio|MRR]] of [[women]] with [[menopause]] at age 40-44 was 1.04%. While the [[Mortality ratio|MRR]] for [[women]] with [[menopause]] at age 45-49 was 0.96%.<ref name="pmid9590601">{{cite journal| author=Cooper GS, Sandler DP| title=Age at natural menopause and mortality. | journal=Ann Epidemiol | year= 1998 | volume= 8 | issue= 4 | pages= 229-35 | pmid=9590601 | doi=10.1016/s1047-2797(97)00207-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9590601  }} </ref>
*The mortality rate ratio (MRR) was 1.50% for women with menopause at age < 40, and the MRR of women with menopause at age 40-44 was 1.04%. While the MRR for women with menopause at age 45-49 was 0.96%.<ref name="pmid9590601">{{cite journal| author=Cooper GS, Sandler DP| title=Age at natural menopause and mortality. | journal=Ann Epidemiol | year= 1998 | volume= 8 | issue= 4 | pages= 229-35 | pmid=9590601 | doi=10.1016/s1047-2797(97)00207-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9590601  }} </ref>


===Race===


====Race====
*The [[prevalence]] of [[menopause]] does not vary by race.
*The prevalence of menopause does not vary by race, but there are several small studies reporting that menopause occurs approximately six months earlier in Black women than White women who have the same age.  
*The [[Ethnic group|ethnic]] differences in the [[symptoms]] experienced during the [[menopausal]] transition were noted. Asian [[women]] had experienced the smallest number of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] compared with all other [[Ethnic group|ethnic groups]], but African American [[women]] had experienced the largest number of [https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 menopausal symptoms] compared with other [[Ethnic group|ethnic groups]].<ref name="pmid19245351">{{cite journal| author=Green R, Santoro N| title=Menopausal symptoms and ethnicity: the Study of Women's Health Across the Nation. | journal=Womens Health (Lond) | year= 2009 | volume= 5 | issue= 2 | pages= 127-33 | pmid=19245351 | doi=10.2217/17455057.5.2.127 | pmc=3270699 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19245351 }} </ref>
*The ethnic differences in the symptoms experienced during the menopausal transition were noted. Asian women had experienced the smallest number of menopausal symptoms compared with all other ethnic groups, but African American women had experienced the largest number of menopausal symptoms compared with other ethnic groups. Brazilian women had experienced highly prevalent and similar vasomotor symptoms like Western women.<ref name="pmid2670463">{{cite journal| author=Tsukamoto T, Sasaki H, Nakamura H| title=Treatment of hemoptysis patients by thrombin and fibrinogen-thrombin infusion therapy using a fiberoptic bronchoscope. | journal=Chest | year= 1989 | volume= 96 | issue= 3 | pages= 473-6 | pmid=2670463 | doi=10.1378/chest.96.3.473 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2670463 }} </ref>





Latest revision as of 07:45, 11 February 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Rahmah Al-Edresi, M.D.[2]


Overview

The prevalence of menopause is estimated to be about 50 million cases annually. Menopause naturally occurs in women between 49 to 52 of age the average. The fatality cases were 345 cases per 3191 women aged between 50-86 years in the United States. There is no racial predilection to Menopause, but African American women had experienced the largest number of menopausal symptoms compared with other ethnic groups.

Epidemiology and Demographics

Prevalence and Incidence


Age

Mortality rate

Race





References

  1. Massart F, Reginster JY, Brandi ML (2001). "Genetics of menopause-associated diseases". Maturitas. 40 (2): 103–16. doi:10.1016/s0378-5122(01)00283-3. PMID 11716989.
  2. Hill K (1996). "The demography of menopause". Maturitas. 23 (2): 113–27. doi:10.1016/0378-5122(95)00968-x. PMID 8735350.
  3. 3.0 3.1 Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P (2010). "Age of menopause and impact of climacteric symptoms by geographical region". Climacteric. 13 (5): 419–28. doi:10.3109/13697137.2010.507886. PMID 20690868.
  4. Sussman M, Trocio J, Best C, Mirkin S, Bushmakin AG, Yood R; et al. (2015). "Prevalence of menopausal symptoms among mid-life women: findings from electronic medical records". BMC Womens Health. 15: 58. doi:10.1186/s12905-015-0217-y. PMC 4542113. PMID 26271251.
  5. Cooper GS, Sandler DP (1998). "Age at natural menopause and mortality". Ann Epidemiol. 8 (4): 229–35. doi:10.1016/s1047-2797(97)00207-x. PMID 9590601.
  6. Green R, Santoro N (2009). "Menopausal symptoms and ethnicity: the Study of Women's Health Across the Nation". Womens Health (Lond). 5 (2): 127–33. doi:10.2217/17455057.5.2.127. PMC 3270699. PMID 19245351.


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