Meningioma other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Other imaging studies for meningioma include magnetic resonance (MR) spectroscopy, magnetic resonance (MR) perfusion, and angiography.[1] MR spectroscopy study for meningioma demonstrates elevated levels of alanine, glutamine, and choline, as well as a significantly reduced levels of N-acetylaspartate and creatine.[1] MR perfusion study for meningioma demonstrates an elevated value of relative cerebral blood volume (rCBV).[2] Angiography of meningioma demonstrates high vascularization of the tumor due to dual blood supply by both pial (intracranial) and meningeal (extracranial) vessels.[1]

Other Imaging Findings

Magnetic resonance spectroscopy

  • Magnetic resonance spectroscopy (MR) spectroscopy imaging may distinguish meningioma from other differential diagnosis. Features include:[1]
  • Elevated alanine level
  • Elevated glutamine/glutamate level
  • Elevated choline (Cho) level
  • Absent or significantly reduced N-acetylaspartate (NAA) level
  • Absent or significantly reduced creatine (Cr) level

Magnetic resonance perfusion

  • Magnetic resonance (MR) perfusion imaging may distinguish meningioma from other differential diagnosis. Features include:[2]
  • Elevated relative cerebral blood volume (rCBV) value
  • Time-intensity curve illustrates a sharp signal drop from baseline with no return to baseline measures

Angiography

  • Angiography of meningioma demonstrates:[1]
  • High vascularization of the tumor due to dual blood supply by both pial (intracranial) and meningeal (extracranial) vessels
  • Spoke wheel appearance
  • Dense venous filling

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References

  1. 1.0 1.1 1.2 1.3 1.4 Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015
  2. 2.0 2.1 Zimny A, Sasiadek M (2011). "Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review". J Neurooncol. 103 (3): 777–83. doi:10.1007/s11060-010-0445-9. PMC 3116130. PMID 21061142.