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{{Medulloblastoma}}
{{Medulloblastoma}}
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==Overview==
==Overview==
Surgical intervention alone is not recommended as a single therapeutic modality for the management of medulloblastoma. According to the risk stratification criterion for medulloblastoma patients, surgery must be followed by the appropriate radiotherapy or chemotherapy management. Surgical excision of medulloblastoma may be done either via  a [[posterior fossa]] craniectomy approach or a suboccipital [[craniectomy]] approach. Complications related to surgery may include [[aseptic meningitis]], [[haematoma]] formation, and posterior fossa syndrome.<ref name="pmid23245832">{{cite journal| author=Bartlett F, Kortmann R, Saran F| title=Medulloblastoma. | journal=Clin Oncol (R Coll Radiol) | year= 2013 | volume= 25 | issue= 1 | pages= 36-45 | pmid=23245832 | doi=10.1016/j.clon.2012.09.008 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23245832  }} </ref>
==Surgery==
==Surgery==
The selection of surgery depends on your cancer stage and general health. If permitted, the neurosurgeons prefer surgery for your medulloblastoma.
* Surgical intervention alone is not recommended as a single therapeutic modality for the management of medulloblastoma.<ref name="pmid23245832">{{cite journal| author=Bartlett F, Kortmann R, Saran F| title=Medulloblastoma. | journal=Clin Oncol (R Coll Radiol) | year= 2013 | volume= 25 | issue= 1 | pages= 36-45 | pmid=23245832 | doi=10.1016/j.clon.2012.09.008 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23245832  }} </ref>
*Radiation therapy: This is a cancer treatment to kill cancer cells or keep them from growing by using high-energy x-rays or other types of radiation.  
* Surgical excision of medulloblastoma may be done either via:
*Chemotherapy: The treatment is to use drugs to stop the growth of cancer cells either by killing the cells or by stopping them from dividing.
:* A [[posterior fossa]] craniectomy approach
:* A suboccipital [[craniectomy]] approach
* The two main objectives of medulloblastoma surgical excision are:
:* Resection of the primary [[brain tumor]] with the least possible postsurgical residual mass
:* Relieve any elevated [[intracranial pressure]] among patients with [[obstructive hydrocephalus]]
* Intraoperative gentle suction of medulloblastoma is preferred over surgical dissection due to the friable nature of the mass.
* A [[ventriculoperitoneal shunt]] may be inserted in 50% of the cases following surgery to manage refractory hydrocephalus.  
* A criticism of pre-operative ventriculoperitoneal shunts is that they may promote the metastatic spread of medulloblastoma.<ref name=surgwiki>Intracranial tumours, infections, and aneurysms. SurgWiki (2015) http://www.surgwiki.com/wiki/Intracranial_tumours,_infection_and_aneurysms#Paediatric_brain_tumours#Management Accessed on October 6, 2015.</ref>
* Surgical complications may include:
:* [[Aseptic meningitis]]
:* Posterior fossa syndrome
:* Cervical instability
:* [[Haematoma]] formation
:* [[GI bleeding]] due to shunt placement


==References==
==References==
{{reflist|2}}
{{reflist|1}}


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Latest revision as of 02:34, 27 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Surgical intervention alone is not recommended as a single therapeutic modality for the management of medulloblastoma. According to the risk stratification criterion for medulloblastoma patients, surgery must be followed by the appropriate radiotherapy or chemotherapy management. Surgical excision of medulloblastoma may be done either via a posterior fossa craniectomy approach or a suboccipital craniectomy approach. Complications related to surgery may include aseptic meningitis, haematoma formation, and posterior fossa syndrome.[1]

Surgery

  • Surgical intervention alone is not recommended as a single therapeutic modality for the management of medulloblastoma.[1]
  • Surgical excision of medulloblastoma may be done either via:
  • The two main objectives of medulloblastoma surgical excision are:
  • Intraoperative gentle suction of medulloblastoma is preferred over surgical dissection due to the friable nature of the mass.
  • A ventriculoperitoneal shunt may be inserted in 50% of the cases following surgery to manage refractory hydrocephalus.
  • A criticism of pre-operative ventriculoperitoneal shunts is that they may promote the metastatic spread of medulloblastoma.[2]
  • Surgical complications may include:

References

  1. 1.0 1.1 Bartlett F, Kortmann R, Saran F (2013). "Medulloblastoma". Clin Oncol (R Coll Radiol). 25 (1): 36–45. doi:10.1016/j.clon.2012.09.008. PMID 23245832.
  2. Intracranial tumours, infections, and aneurysms. SurgWiki (2015) http://www.surgwiki.com/wiki/Intracranial_tumours,_infection_and_aneurysms#Paediatric_brain_tumours#Management Accessed on October 6, 2015.


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