Medulloblastoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Incidence

Brain tumors are the second most common malignancy among children less than 20 years of age. Medulloblastoma is the most common malignant brain tumor, comprising 14.5% of newly diagnosed cases.[1] In adults, medulloblastoma is rare, comprising less than 2% of CNS malignancies.[2]

The incidence of childhood medulloblastoma is higher in males (62%) than females (38%). [3] Medulloblastoma and other PNET tumors are more prevalent in younger children than older children. 40% of medulloblastoma patients are diagnosed before the age of 5, 31% are between the ages of 5 and 9, 18.3% are between the ages of 10 and 14, and 12.7% are between the ages of 15 and 19. [4]

References

  1. James G. Gurney, Malcolm A. Smith, Greta R. Bunin, CNS and Miscellaneous Intracranial and Intraspinal Neoplasms, SEER Pediatric Monograph, National Cancer Institute
  2. Selected Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates, Central Brain Tumor Registry of the United States, 1998-2002.
  3. Selected Childhood Primary Brain and Central Nervous System Tumor Incidence Rates by Major Histology Groupings, Histology and Gender Central Brain Tumor Registry of the United States, 1998-2002.
  4. Selected Childhood Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates, Central Brain Tumor Registry of the United States, 1998-2002.


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