Maspin

Serpin peptidase inhibitor, clade B (ovalbumin), member 5
PDB rendering based on 1wz9.
Identifiers
Symbols	SERPINB5 ; PI5; maspin
External IDs	Template:OMIM5 Template:MGI HomoloGene: 20580
Gene ontology Molecular function Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

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List of terms related to Maspin

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Maspin is a serpin and tumor suppressor gene.

Further reading

• Sager R, Sheng S, Pemberton P, Hendrix MJ (1998). "Maspin. A tumor suppressing serpin". Adv. Exp. Med. Biol. 425: 77–88. PMID 9433491.CS1 maint: Multiple names: authors list (link)
• Sheng S (2006). "The promise and challenge toward the clinical application of maspin in cancer". Front. Biosci. 9: 2733–45. PMID 15353310.
• Lockett J, Yin S, Li X; et al. (2006). "Tumor suppressive maspin and epithelial homeostasis". J. Cell. Biochem. 97 (4): 651–60. doi:10.1002/jcb.20721. PMID 16329135.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen EI, Yates JR (2006). "Maspin and tumor metastasis". IUBMB Life. 58 (1): 25–9. doi:10.1080/15216540500531721. PMID 16540429.
• Khalkhali-Ellis Z (2007). "Maspin: the new frontier". Clin. Cancer Res. 12 (24): 7279–83. doi:10.1158/1078-0432.CCR-06-1589. PMID 17189399.
• Schneider SS, Schick C, Fish KE; et al. (1995). "A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene". Proc. Natl. Acad. Sci. U.S.A. 92 (8): 3147–51. PMID 7724531.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pemberton PA, Wong DT, Gibson HL; et al. (1995). "The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin". J. Biol. Chem. 270 (26): 15832–7. PMID 7797587.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zou Z, Anisowicz A, Hendrix MJ; et al. (1994). "Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells". Science. 263 (5146): 526–9. PMID 8290962.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pemberton PA, Tipton AR, Pavloff N; et al. (1998). "Maspin is an intracellular serpin that partitions into secretory vesicles and is present at the cell surface". J. Histochem. Cytochem. 45 (12): 1697–706. PMID 9389773.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xia W, Lau YK, Hu MC; et al. (2000). "High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma". Oncogene. 19 (20): 2398–403. doi:10.1038/sj.onc.1203535. PMID 10828881.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Biliran H, Sheng S (2002). "Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin". Cancer Res. 61 (24): 8676–82. PMID 11751384.
• Blacque OE, Worrall DM (2002). "Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen". J. Biol. Chem. 277 (13): 10783–8. doi:10.1074/jbc.M110992200. PMID 11788595.
• Dokras A, Gardner LM, Kirschmann DA; et al. (2002). "The tumour suppressor gene maspin is differentially regulated in cytotrophoblasts during human placental development". Placenta. 23 (4): 274–80. doi:10.1053/plac.2001.0784. PMID 11969337.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jiang N, Meng Y, Zhang S; et al. (2002). "Maspin sensitizes breast carcinoma cells to induced apoptosis". Oncogene. 21 (26): 4089–98. doi:10.1038/sj.onc.1205507. PMID 12037665.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Odero-Marah VA, Khalkhali-Ellis Z, Schneider GB; et al. (2002). "Tyrosine phosphorylation of maspin in normal mammary epithelia and breast cancer cells". Biochem. Biophys. Res. Commun. 295 (4): 800–5. PMID 12127964.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maass N, Biallek M, Rösel F; et al. (2002). "Hypermethylation and histone deacetylation lead to silencing of the maspin gene in human breast cancer". Biochem. Biophys. Res. Commun. 297 (1): 125–8. PMID 12220518.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sood AK, Fletcher MS, Gruman LM; et al. (2002). "The paradoxical expression of maspin in ovarian carcinoma". Clin. Cancer Res. 8 (9): 2924–32. PMID 12231537.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Son HJ, Sohn TS, Song SY; et al. (2003). "Maspin expression in human gastric adenocarcinoma". Pathol. Int. 52 (8): 508–13. PMID 12366809.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bass R, Fernández AM, Ellis V (2003). "Maspin inhibits cell migration in the absence of protease inhibitory activity". J. Biol. Chem. 277 (49): 46845–8. doi:10.1074/jbc.C200532200. PMID 12384513.CS1 maint: Multiple names: authors list (link)

External links

• maspin at the US National Library of Medicine Medical Subject Headings (MeSH)

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