Kawasaki disease epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
Kawasaki disease occurs worldwide, with the highest incidence in Japan, and it most often affects boys and younger children. KS may have a winter-spring seasonality, and community-wide outbreaks have been reported occasionally. In the continental United States, population-based and hospitalization studies have estimated an incidence of KS ranging from 9 to 19 per 100,000 children younger than 5 years of age. Approximately 4248 hospitalizations for Kawasaki disease, of which 3277 (77%) were for children under 5 years of age, were estimated among children younger than 18 years of age in the United States in the year 2000. | Kawasaki disease (Kawasaki syndrome or KS) occurs worldwide, with the highest incidence in Japan, and it most often affects boys and younger children. KS may have a winter-spring seasonality, and community-wide outbreaks have been reported occasionally. In the continental United States, population-based and hospitalization studies have estimated an incidence of KS ranging from 9 to 19 per 100,000 children younger than 5 years of age. Approximately 4248 hospitalizations for Kawasaki disease, of which 3277 (77%) were for children under 5 years of age, were estimated among children younger than 18 years of age in the United States in the year 2000. | ||
== Epidemiology and Demographics == | == Epidemiology and Demographics == | ||
Kawasaki disease occurs worldwide, with the highest incidence in Japan, and it most often affects boys and younger children. KS may have a winter-spring seasonality, and community-wide outbreaks have been reported occasionally. In the continental United States, population-based and hospitalization studies have estimated an incidence of KS ranging from 9 to 19 per 100,000 children younger than 5 years of age. Approximately 4248 hospitalizations for Kawasaki disease, of which 3277 (77%) were for children under 5 years of age, were estimated among children younger than 18 years of age in the United States in the year 2000.<ref name="urlAbout Kawasaki Disease | Kawasaki Disease | CDC">{{cite web |url=https://www.cdc.gov/kawasaki/about.html |title=About Kawasaki Disease | Kawasaki Disease | CDC |format= |work= |accessdate=}}</ref> | Kawasaki disease occurs worldwide, with the highest incidence in Japan, and it most often affects boys and younger children. KS may have a winter-spring seasonality, and community-wide outbreaks have been reported occasionally. In the continental United States, population-based and hospitalization studies have estimated an incidence of KS ranging from 9 to 19 per 100,000 children younger than 5 years of age. Approximately 4248 hospitalizations for Kawasaki disease, of which 3277 (77%) were for children under 5 years of age, were estimated among children younger than 18 years of age in the United States in the year 2000.<ref name="urlAbout Kawasaki Disease | Kawasaki Disease | CDC">{{cite web |url=https://www.cdc.gov/kawasaki/about.html |title=About Kawasaki Disease | Kawasaki Disease | CDC |format= |work= |accessdate=}}</ref> | ||
Revision as of 19:36, 16 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]
Overview
Kawasaki disease (Kawasaki syndrome or KS) occurs worldwide, with the highest incidence in Japan, and it most often affects boys and younger children. KS may have a winter-spring seasonality, and community-wide outbreaks have been reported occasionally. In the continental United States, population-based and hospitalization studies have estimated an incidence of KS ranging from 9 to 19 per 100,000 children younger than 5 years of age. Approximately 4248 hospitalizations for Kawasaki disease, of which 3277 (77%) were for children under 5 years of age, were estimated among children younger than 18 years of age in the United States in the year 2000.
Epidemiology and Demographics
Kawasaki disease occurs worldwide, with the highest incidence in Japan, and it most often affects boys and younger children. KS may have a winter-spring seasonality, and community-wide outbreaks have been reported occasionally. In the continental United States, population-based and hospitalization studies have estimated an incidence of KS ranging from 9 to 19 per 100,000 children younger than 5 years of age. Approximately 4248 hospitalizations for Kawasaki disease, of which 3277 (77%) were for children under 5 years of age, were estimated among children younger than 18 years of age in the United States in the year 2000.[1]
CDC uses hospital discharge data, a passive KS surveillance system, and special studies to describe the incidence and epidemiology of KS in the United States. The KS surveillance system has been maintained by CDC since 1976 and is based on voluntary reporting of KS cases by health care providers and local and state health authorities. A standardized case report form is used to collect information on patients.
For epidemiologic surveillance, CDC defines a case of KS as illness in a patient with fever of 5 or more days duration (or fever until the date of administration of intravenous immunoglobulin if it is given before the fifth day of fever), and the presence of at least 4 of the following 5 clinical signs:[2]
- Rash
- Cervical lymphadenopathy (at least 1.5 cm in diameter)
- Bilateral conjuctival injection
- Oral mucosal changes
- Peripheral extremity changes.
Patients whose illness does not meet the above KS case definition but who have fever and coronary artery abnormalities are classified as having atypical or incomplete KS.
Incidence
- The incidence of Kawasaki disease is approximately 175 per 100,000 individuals in Japan.[3]
- The incidence of Kawasaki disease in the United States is increasing, the additional risk factors in the United States are asian race and male sex.
- 80% of patients with Kawasaki disease are younger than 5 years of age
Prevalence
- In 1999, the prevalence of Kawasaki disease was estimated to be in range of 5000 to 6000 in Japan.[4]
References
- ↑ "About Kawasaki Disease | Kawasaki Disease | CDC".
- ↑ Assadian A, Assadian O, Simon A, Kramer A (December 2009). "Infection control consequences - early Staphylococcal Scalded Skin Syndrome or Kawasaki Syndrome?". GMS Krankenhhyg Interdiszip. 4 (2): Doc05. doi:10.3205/dgkh000130. PMC 2831247. PMID 20204087.
- ↑ Kawasaki T (March 1967). "[Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children]". Arerugi (in Japanese). 16 (3): 178–222. PMID 6062087.
- ↑ Yanagawa H, Nakamura Y, Ojima T, Yashiro M, Tanihara S, Oki I (January 1999). "Changes in epidemic patterns of Kawasaki disease in Japan". Pediatr. Infect. Dis. J. 18 (1): 64–6. PMID 9951983.