Kaposi's sarcoma differential diagnosis: Difference between revisions
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|Diseases | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases | ||
|Etiology | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology | ||
|Congenital | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital | ||
|Acquired | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquired | ||
|Demography | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography | ||
!Appearance | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance | ||
!Fever | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever | ||
!Bleeding | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bleeding | ||
!BP | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP | ||
!Hepatosplenomegaly | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly | ||
!Lymphadenopathy | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy | ||
!Other | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other | ||
!WBC | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC | ||
!Hb | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hb | ||
!Plt | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt | ||
|LFT | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT | ||
|ESR/CRP | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP | ||
|Histopathology | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology | ||
|Gold standard diagnosis | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard diagnosis | ||
|Associated findings | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Masson's [[hemangioma]] <ref name="pmid22993679">{{cite journal |vauthors=Park KK, Won YS, Yang JY, Choi CS, Han KY |title=Intravascular Papillary Endothelial Hyperplasia (Masson tumor) of the Skull : Case Report and Literature Review |journal=J Korean Neurosurg Soc |volume=52 |issue=1 |pages=52–4 |date=July 2012 |pmid=22993679 |pmc=3440504 |doi=10.3340/jkns.2012.52.1.52 |url=}}</ref> | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Masson's [[hemangioma]] <ref name="pmid22993679">{{cite journal |vauthors=Park KK, Won YS, Yang JY, Choi CS, Han KY |title=Intravascular Papillary Endothelial Hyperplasia (Masson tumor) of the Skull : Case Report and Literature Review |journal=J Korean Neurosurg Soc |volume=52 |issue=1 |pages=52–4 |date=July 2012 |pmid=22993679 |pmc=3440504 |doi=10.3340/jkns.2012.52.1.52 |url=}}</ref> | ||
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* [[Visual field loss|Visual field deficits]] | * [[Visual field loss|Visual field deficits]] | ||
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|Diseases | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases | ||
|Etiology | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology | ||
|Congenital | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital | ||
|Acquired | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquired | ||
|Demography | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography | ||
!Appearance | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance | ||
!Fever | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever | ||
!Bleeding | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bleeding | ||
!BP | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP | ||
!Hepatosplenomegaly | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly | ||
!Lymphadenopathy | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy | ||
!Other | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other | ||
!WBC | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC | ||
!Hb | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hb | ||
!Plt | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt | ||
|LFT | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT | ||
|ESR/CRP | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP | ||
|Histopathology | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology | ||
|Gold standard diagnosis | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard diagnosis | ||
|Associated findings | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings | ||
|} | |} | ||
Revision as of 17:42, 4 October 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2] Haytham Allaham, M.D. [3]
Kaposi's sarcoma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Kaposi's sarcoma differential diagnosis On the Web |
American Roentgen Ray Society Images of Kaposi's sarcoma differential diagnosis |
Risk calculators and risk factors for Kaposi's sarcoma differential diagnosis |
Overview
Kaposi's sarcoma must be differentiated from other diseases that cause similar cutaneous, pulmonary, and gastrointestinal involvement, such as bacillary angiomatosis, AIDS-related lymphoma, and seborrheic keratosis.
Differentiating Kaposi's Sarcoma from other Diseases
- Kaposi's sarcoma must be differentiated from other diseases that cause similar cutaneous, pulmonary, and gastrointestinal involvement.[1][2][3]
Diseases | Etiology | Congenital | Acquired | Demography | Clinical manifestations | Lab findings | Gold standard diagnosis | Associated findings | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms | Signs | CBC | LFT | ESR/CRP | Histopathology | ||||||||||||||
Appearance | Fever | Bleeding | BP | Hepatosplenomegaly | Lymphadenopathy | Other | WBC | Hb | Plt | ||||||||||
Bacillary angiomatosis [4] | – | + | Any age, usually between 20 -50 years | Solitary or multiple red, purple, flesh-colored, or colorless papules | ± | ± | Nl | – | – | Nl | Nl | Nl | Nl | Nl |
|
Clinical manifestation | |||
Arteriovenous malformation [5] |
|
+ | – | Any age | Nl | – | + | Nl | – | – | Nl | Nl | Nl | Nl | Nl | NA | Imaging | ||
Acroangiodermatitis[6] |
|
– | – | Any age, more in males | Purplish-blue to brown papules and plaques | – | – | Nl | – | – |
|
Nl | Nl | Nl | Nl | Nl |
|
Clinical manifesttations | |
Angiosarcoma [7] |
|
– | – | Adults, more in males | Enlarging bruise, a blue-black nodule, or an unhealed ulceration | – | – | Nl | – | – | – | Nl | ↓ | ↓ | Nl | Nl |
|
Biopsy | NA |
Diseases | Etiology | Congenital | Acquired | Demography | Appearance | Fever | Bleeding | BP | Hepatosplenomegaly | Lymphadenopathy | Other | WBC | Hb | Plt | LFT | ESR/CRP | Histopathology | Gold standard diagnosis | Associated findings |
Masson's hemangioma [8] |
|
– | – | Rare |
|
– | – | Nl | – | – | – | Nl | Nl | Nl | Nl | Nl |
|
Biopsy | |
Seborrheic keratosis [9] |
|
+ | – | Any age |
|
– | – | Nl | – | – | – | Nl | Nl | Nl | Nl | Nl |
|
Clinical manifestations |
|
Systemic lupus erythematosus (SLE) [10] |
|
– | – | More common in female, typically in the 20 to 30 years |
|
± | - | ↑ | ± | ± | ↑ | ↓ | ↓ | Nl | Nl |
|
Clinical manifestations | ||
Pyogenic granuloma [11] |
|
+ | + | Any age, usually in 20-30 years |
|
– | + | Nl | – | – | – | Nl | Nl | Nl | Nl | Nl |
|
Clinical manifestation | NA |
Benign lymphangioendothelioma [12] |
|
– | + | Any ages, median age is 50 years | – | – | Nl | – | – | – | Nl | Nl | Nl | Nl | Nl |
|
Biopsy | NA | |
Cavernous hemangioma [13] |
|
– | – | Usually in third to fifth decades of life. |
|
– | – | Nl | – | – | – | Nl | Nl | Nl | Nl | Nl |
|
Clinical manidestation |
|
Diseases | Etiology | Congenital | Acquired | Demography | Appearance | Fever | Bleeding | BP | Hepatosplenomegaly | Lymphadenopathy | Other | WBC | Hb | Plt | LFT | ESR/CRP | Histopathology | Gold standard diagnosis | Associated findings |
References
- ↑ Kaposi's Sarcoma. Radiopaedia (2015) http://radiopaedia.org/articles/kaposi-sarcoma Accessed on January, 19 2016
- ↑ Libre Pathology. Kaposi's sarcoma (2015) http://librepathology.org/wiki/index.php/File:Kaposi_sarcoma_low_intermed_mag.jpg Accessed on January, 19 2016
- ↑ Kaposi's Sarcoma. PathologyOutlines (2015) http://www.pathologyoutlines.com/topic/skintumornonmelanocytickaposisarcoma.html Accessed on January, 19 2015
- ↑ Tappero JW, Perkins BA, Wenger JD, Berger TG (July 1995). "Cutaneous manifestations of opportunistic infections in patients infected with human immunodeficiency virus". Clin. Microbiol. Rev. 8 (3): 440–50. PMC 174635. PMID 7553576.
- ↑ Whitehead KJ, Smith MC, Li DY (February 2013). "Arteriovenous malformations and other vascular malformation syndromes". Cold Spring Harb Perspect Med. 3 (2): a006635. doi:10.1101/cshperspect.a006635. PMC 3552339. PMID 23125071.
- ↑ Lugović L, Pusić J, Situm M, Buljan M, Bulat V, Sebetić K, Soldo-Belić A (2007). "Acroangiodermatitis (pseudo-Kaposi sarcoma): three case reports". Acta Dermatovenerol Croat. 15 (3): 152–7. PMID 17868541.
- ↑ Barttelbort SW, Stahl R, Ariyan S (July 1989). "Cutaneous angiosarcoma of the face and scalp". Plast. Reconstr. Surg. 84 (1): 55–9. PMID 2734404.
- ↑ Park KK, Won YS, Yang JY, Choi CS, Han KY (July 2012). "Intravascular Papillary Endothelial Hyperplasia (Masson tumor) of the Skull : Case Report and Literature Review". J Korean Neurosurg Soc. 52 (1): 52–4. doi:10.3340/jkns.2012.52.1.52. PMC 3440504. PMID 22993679.
- ↑ Noiles K, Vender R (2008). "Are all seborrheic keratoses benign? Review of the typical lesion and its variants". J Cutan Med Surg. 12 (5): 203–10. doi:10.2310/7750.2008.07096. PMID 18845088.
- ↑ Uva L, Miguel D, Pinheiro C, Freitas JP, Marques Gomes M, Filipe P (2012). "Cutaneous manifestations of systemic lupus erythematosus". Autoimmune Dis. 2012: 834291. doi:10.1155/2012/834291. PMC 3410306. PMID 22888407.
- ↑ Kamal R, Dahiya P, Puri A (January 2012). "Oral pyogenic granuloma: Various concepts of etiopathogenesis". J Oral Maxillofac Pathol. 16 (1): 79–82. doi:10.4103/0973-029X.92978. PMC 3303528. PMID 22434943.
- ↑ Guillou L, Fletcher CD (August 2000). "Benign lymphangioendothelioma (acquired progressive lymphangioma): a lesion not to be confused with well-differentiated angiosarcoma and patch stage Kaposi's sarcoma: clinicopathologic analysis of a series". Am. J. Surg. Pathol. 24 (8): 1047–57. PMID 10935645.
- ↑ Goldberg RE, Pheasant TR, Shields JA (December 1979). "Cavernous hemangioma of the retina. A four-generation pedigree with neurocutaneous manifestations and an example of bilateral retinal involvement". Arch. Ophthalmol. 97 (12): 2321–4. PMID 229814.