Gestational trophoblastic neoplasia staging: Difference between revisions
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{{Gestational trophoblastic neoplasia}} | {{Gestational trophoblastic neoplasia}} | ||
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{{CMG}}{{AE}}{{MD}} | {{CMG}}{{AE}}{{MD}} | ||
==Overview== | ==Overview== | ||
According to the Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) [[cancer staging]] system, there are 4 stages of | According to the Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) [[cancer staging]] system, there are 4 stages of gestational trophoblastic neoplasia (GTN).<ref name="eee">Stage Information for Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq#section/_11 URL Accessed on October 7, 2015</ref> | ||
==Staging== | ==Staging== | ||
'''The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) staging system''' <ref name= eee>Stage Information for Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq#section/_11 URL Accessed on October 7, 2015</ref> | '''The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) staging system''' <ref name="eee">Stage Information for Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq#section/_11 URL Accessed on October 7, 2015</ref> | ||
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I | I | ||
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Disease confined to the uterus | [[Disease]] confined to the [[uterus]] | ||
|- | |- | ||
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II | II | ||
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GTN extends outside of the uterus, but is limited to the genital structures (adnexa, vagina, broad ligament) | GTN extends outside of the [[uterus]], but is limited to the genital structures ([[adnexa]], [[vagina]], [[Broad ligament of the uterus|broad ligament]]) | ||
|- | |- | ||
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III | III | ||
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GTN extends to the lungs, with or without known genital tract involvement | GTN extends to the [[Lung|lungs]], with or without known [[Urinary system|genital tract]] involvement | ||
|- | |- | ||
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IV | IV | ||
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All other metastatic sites | All other [[Metastasis|metastatic]] sites | ||
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Revision as of 20:09, 11 March 2019
Gestational trophoblastic neoplasia Microchapters |
Differentiating Gestational trophoblastic neoplasia from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Gestational trophoblastic neoplasia staging On the Web |
American Roentgen Ray Society Images of Gestational trophoblastic neoplasia staging |
Directions to Hospitals Treating Gestational trophoblastic neoplasia |
Risk calculators and risk factors for Gestational trophoblastic neoplasia staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
According to the Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) cancer staging system, there are 4 stages of gestational trophoblastic neoplasia (GTN).[1]
Staging
The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) staging system [1]
Stage | FIGO Anatomical Staging |
---|---|
I |
|
II |
GTN extends outside of the uterus, but is limited to the genital structures (adnexa, vagina, broad ligament) |
III |
GTN extends to the lungs, with or without known genital tract involvement |
IV |
All other metastatic sites |
Modified WHO prognostic scoring system as adapted by Fédération Internationale de Gynécologie et d'Obstétrique (FIGO)[2]
Score | 0 | 1 | 3 | 4 |
---|---|---|---|---|
Age | < 40 | 40 | - | - |
Antecedent pregnancy | Mole | Abortion | Term | - |
Interval months from index pregnancy | < 4 | 4 - < 7 | 7 - < 13 | ≥ 13 |
Pre-treatment serum βhCG
(iu/l) |
< 103 | 103 - < 104 | 104 - < 105 | ≥ 105 |
Largest tumor size (including uterus) | - | 3 - < 5 cm | ≥ 5cm | - |
Site of metastases | Lung | Spleen, Kidney | Gastrointestinal | Liver, Brain |
Number of metastases | - | 1 - 4 | 5 - 8 | > 8 |
Previous failed chemotherapy | - | - | 1 drug | 2 or more drugs |
References
- ↑ 1.0 1.1 Stage Information for Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq#section/_11 URL Accessed on October 7, 2015
- ↑ Ngan HY, Bender H, Benedet JL, Jones H, Montruccoli GC, Pecorelli S (October 2003). "Gestational trophoblastic neoplasia, FIGO 2000 staging and classification". Int J Gynaecol Obstet. 83 Suppl 1: 175–7. PMID 14763174.