Extranodal NK-T-cell lymphoma staging: Difference between revisions
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==Staging== | ==Staging== | ||
* Extranodal NK/T cell lymphoma survival rate is not well predicted by [[Ann Arbor staging system]]. | * Extranodal NK/T cell lymphoma survival rate is not well predicted by [[Ann Arbor staging system]]<ref name="pmid12876666">{{cite journal| author=Jaffe ES, Krenacs L, Raffeld M| title=Classification of cytotoxic T-cell and natural killer cell lymphomas. | journal=Semin Hematol | year= 2003 | volume= 40 | issue= 3 | pages= 175-84 | pmid=12876666 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12876666 }}</ref>. | ||
*A new system was introduced by a Korean study based on [[B symptoms]], [[Ann Arbor Staging|Ann Arbor system]], [[LDH]] level, and regional [[lymphadenopathy]] combined.Four risk groups identified as below: | *A new system was introduced by a Korean study based on [[B symptoms]], [[Ann Arbor Staging|Ann Arbor system]], [[LDH]] level, and regional [[lymphadenopathy]] combined.Four risk groups identified as below: | ||
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* Another parallel mechanism for extranodal NK/T cell lymphoma is based on [[tumor]] [[Biology|biologic]] and micro-environmental factors. High Ki-67 [[nuclear]] antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk. | * Another parallel mechanism for extranodal NK/T cell lymphoma is based on [[tumor]] [[Biology|biologic]] and micro-environmental factors. High Ki-67 [[nuclear]] antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk. | ||
==References== | ==References== | ||
Revision as of 13:54, 2 October 2019
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Extranodal NK-T-cell lymphoma Microchapters |
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Differentiating Extranodal NK-T-cell lymphoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Extranodal NK-T-cell lymphoma staging On the Web |
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American Roentgen Ray Society Images of Extranodal NK-T-cell lymphoma staging |
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Risk calculators and risk factors for Extranodal NK-T-cell lymphoma staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]
Overview
Extranodal NK/T cell lymphoma survival rate is not well predicted by Ann Arbor staging system. A new system was introduced based on B symptoms, Ann Arbor system, LDH level, and regional lymphadenopathy combined. Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors. High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk.
Staging
- Extranodal NK/T cell lymphoma survival rate is not well predicted by Ann Arbor staging system[1].
- A new system was introduced by a Korean study based on B symptoms, Ann Arbor system, LDH level, and regional lymphadenopathy combined.Four risk groups identified as below:
- group 1: No adverse factor
- group 2: One factor
- group 3: Two factors
- group 4: Three or more factors
| Group | Altered factors count | 5 year prognosis |
|---|---|---|
| 1 | N.O. | 81000 out of 100000 |
| 2 | 1 | 64000 out of 100000 |
| 3 | 2 | 34000 out of 100000 |
| 4 | 3/More | 7000 out of 100000 |
- Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors. High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk.
References
- ↑ Jaffe ES, Krenacs L, Raffeld M (2003). "Classification of cytotoxic T-cell and natural killer cell lymphomas". Semin Hematol. 40 (3): 175–84. PMID 12876666.