Extranodal NK-T-cell lymphoma staging: Difference between revisions
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{{CMG}}; {{AE}} {{RG}} | {{CMG}}; {{AE}} {{RG}} | ||
==Overview== | ==Overview== | ||
Extranodal NK/T cell lymphoma survival rate is not well predicted by [[Ann Arbor staging system]]. A new system was introduced based on [[B symptoms]], [[Ann Arbor Staging|Ann Arbor system]], [[LDH]] level, and regional [[lymphadenopathy]] combined. Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors. High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk. | |||
==Staging== | ==Staging== | ||
Extranodal NK/T cell lymphoma survival rate is not well predicted by [[Ann Arbor staging system]]. | |||
* Extranodal NK/T cell lymphoma survival rate is not well predicted by [[Ann Arbor staging system]]. A new system was introduced by a Korean study based on [[B symptoms]], [[Ann Arbor Staging|Ann Arbor system]], [[LDH]] level, and regional [[lymphadenopathy]] combined.Four risk groups identified as below: | |||
# group 1: No adverse factor | # group 1: No adverse factor | ||
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| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | 7000 out of 100000 | | style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | 7000 out of 100000 | ||
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* Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors.<ref name="KimHeo2009">{{cite journal|last1=Kim|first1=Tae Min|last2=Heo|first2=Dae Seog|title=Extranodal NK / T-cell lymphoma, nasal type: New staging system and treatment strategies|journal=Cancer Science|volume=100|issue=12|year=2009|pages=2242–2248|issn=13479032|doi=10.1111/j.1349-7006.2009.01319.x}}</ref> High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk. | |||
==References== | ==References== | ||
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[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Immunology]] | [[Category:Immunology]] | ||
<references /> | |||
Revision as of 15:09, 27 August 2019
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Extranodal NK-T-cell lymphoma Microchapters |
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Differentiating Extranodal NK-T-cell lymphoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Extranodal NK-T-cell lymphoma staging On the Web |
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American Roentgen Ray Society Images of Extranodal NK-T-cell lymphoma staging |
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Risk calculators and risk factors for Extranodal NK-T-cell lymphoma staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]
Overview
Extranodal NK/T cell lymphoma survival rate is not well predicted by Ann Arbor staging system. A new system was introduced based on B symptoms, Ann Arbor system, LDH level, and regional lymphadenopathy combined. Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors. High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk.
Staging
- Extranodal NK/T cell lymphoma survival rate is not well predicted by Ann Arbor staging system. A new system was introduced by a Korean study based on B symptoms, Ann Arbor system, LDH level, and regional lymphadenopathy combined.Four risk groups identified as below:
- group 1: No adverse factor
- group 2: One factor
- group 3: Two factors
- group 4: Three or more factors
| Group | Altered factors count | 5 year prognosis |
|---|---|---|
| 1 | N.O. | 81000 out of 100000 |
| 2 | 1 | 64000 out of 100000 |
| 3 | 2 | 34000 out of 100000 |
| 4 | 3/More | 7000 out of 100000 |
- Another parallel mechanism for extranodal NK/T cell lymphoma is based on tumor biologic and micro-environmental factors.[1] High Ki-67 nuclear antigen is a marker for actively proliferation tumor cell which could be a related factor with mass bulk.