Esthesioneuroblastoma differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Esthesioneuroblastoma must be differentiated from other tumors with similar histological appearance, such as lymphoma, Ewing sarcoma, melanoma, olfactory/ other [rhabdomyosarcoma or Merkel cell carcinoma], neuroblastoma, and small cell carcinoma.
Differential Diagnosis
The differential diagnosis of esthesioneuroblastoma includes the following:
- Olfactory neuroepithelioma
- Olfactory groove meningioma/haemangiopericytoma
- Sinonasal carcinoma (including SCC, minor salivary gland adenocarcinoma)
- Rhabdomyosarcoma
- Melanoma metastases
- Lymphoma
- Chordoma
- Juvenile nasopharyngeal angiofibroma
- Pituitary macroadenoma
- The following list describes the outcome of each of these diseases with various immunohistochemical tests.
- Distinguishing esthesioneuroblastomas from the other tumors is of paramount importance because the tumors respond differently to various treatment modalities.
Disease | Immunohistochemical Tests |
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