Esthesioneuroblastoma other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Other imaging studies for esthesioneuroblastoma include angiography/digital subtraction angiography, nuclear medicine, nasal endoscopy, and scintigraphy.[1]

Other Imaging Findings

Other imaging studies for esthesioneuroblastoma include angiography/digital subtraction angiography and nuclear medicine.[1]

Angiography/Digital subtraction angiography (DSA)

Angiography demonstrates a prominent tumor blush with arteriovenous shunting, and persistent opacification.

Nuclear Medicine

As with other neuroblastomas, olfactory neuroblastomas are -meta-iodobenzylguanidine, MIBG avid. This potentially helps to differentiate them from other tumors that arise in the region.

Nasal Endoscopy

Nasal endoscopy is helpful for evaluating tumor location, extent and characteristics, as well as for obtaining a biopsy.

Scintigraphy

Since the majority of esthesioneuroblastomas express somatostatin receptors, the use of scintigraphy with a radiolabeled somatostatin analog (111 In-pentoctreotide [111 In-DTPA-D-pheoctreotide]; Octreoscan) has been postulated. This technique has been found to be clinically useful, especially for discriminating between postoperative changes and recurrent or residual tumor after extensive skull base surgery.[2]

References

  1. 1.0 1.1 Esthesioneuroblastoma. Radiopedia(2015) http://radiopaedia.org/articles/olfactory-neuroblastoma Accessed on January 25, 2016
  2. Rostomily RC, Elias M, Deng M, Elias P, Born DE, Muballe D; et al. (2006). "Clinical utility of somatostatin receptor scintigraphic imaging (octreoscan) in esthesioneuroblastoma: a case study and survey of somatostatin receptor subtype expression". Head Neck. 28 (4): 305–12. doi:10.1002/hed.20356. PMID 16470879.

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