Esthesioneuroblastoma differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Esthesioneuroblastoma must be differentiated from other tumors with similar histological appearance, such as lymphoma, Ewing sarcoma, melanoma, olfactory/ other [rhabdomyosarcoma or Merkel cell carcinoma] | Esthesioneuroblastoma must be differentiated from other tumors with similar histological appearance, such as [[lymphoma]], [[Ewing sarcoma]], [[melanoma]], olfactory/ other ([[rhabdomyosarcoma]] or [[Merkel cell carcinoma]]) [[neuroblastoma]], and small cell carcinoma. Distinguishing esthesioneuroblastomas from the other [[tumors]] is of paramount importance because the tumors respond differently to various treatment modalities.<ref name="radio"> Esthesioneuroblastoma. Radiopedia(2015) http://radiopaedia.org/articles/olfactory-neuroblastoma Accessed on January 25, 2016</ref><ref name="pmid9580174">{{cite journal| author=Argani P, Perez-Ordoñez B, Xiao H, Caruana SM, Huvos AG, Ladanyi M| title=Olfactory neuroblastoma is not related to the Ewing family of tumors: absence of EWS/FLI1 gene fusion and MIC2 expression. | journal=Am J Surg Pathol | year= 1998 | volume= 22 | issue= 4 | pages= 391-8 | pmid=9580174 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9580174 }} </ref> | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
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*Olfactory groove meningioma/haemangiopericytoma | *Olfactory groove meningioma/haemangiopericytoma | ||
*Sinonasal carcinoma (including SCC, minor salivary gland adenocarcinoma) | *Sinonasal carcinoma (including SCC, minor salivary gland adenocarcinoma) | ||
*Rhabdomyosarcoma | *[[Rhabdomyosarcoma]] | ||
*Melanoma metastases | *[[Melanoma]] [[metastases]] | ||
*Lymphoma | *[[Lymphoma]] | ||
*Chordoma | *[[Chordoma]] | ||
*Juvenile nasopharyngeal angiofibroma | *[[Juvenile nasopharyngeal angiofibroma]] | ||
*Pituitary macroadenoma | *[[Pituitary macroadenoma]] | ||
Revision as of 16:03, 27 January 2016
Esthesioneuroblastoma Microchapters | |
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Risk calculators and risk factors for Esthesioneuroblastoma differential diagnosis | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Esthesioneuroblastoma must be differentiated from other tumors with similar histological appearance, such as lymphoma, Ewing sarcoma, melanoma, olfactory/ other (rhabdomyosarcoma or Merkel cell carcinoma) neuroblastoma, and small cell carcinoma. Distinguishing esthesioneuroblastomas from the other tumors is of paramount importance because the tumors respond differently to various treatment modalities.[1][2]
Differential Diagnosis
The differential diagnosis of esthesioneuroblastoma includes the following:[1][2]
- Olfactory neuroepithelioma
- Olfactory groove meningioma/haemangiopericytoma
- Sinonasal carcinoma (including SCC, minor salivary gland adenocarcinoma)
- Rhabdomyosarcoma
- Melanoma metastases
- Lymphoma
- Chordoma
- Juvenile nasopharyngeal angiofibroma
- Pituitary macroadenoma
The outcome of following diseases with various immunohistochemical tests is shown below in a tabular form:
Disease | Immunohistochemical Tests |
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References
- ↑ 1.0 1.1 Esthesioneuroblastoma. Radiopedia(2015) http://radiopaedia.org/articles/olfactory-neuroblastoma Accessed on January 25, 2016
- ↑ 2.0 2.1 Argani P, Perez-Ordoñez B, Xiao H, Caruana SM, Huvos AG, Ladanyi M (1998). "Olfactory neuroblastoma is not related to the Ewing family of tumors: absence of EWS/FLI1 gene fusion and MIC2 expression". Am J Surg Pathol. 22 (4): 391–8. PMID 9580174.