Esophageal cancer pathophysiology: Difference between revisions

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{{Esophageal cancer}}
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==Overview==
==Overview==
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==Pathophysiology==
==Pathophysiology==
====Microscopic pathology====
====Microscopic pathology====
Most tumors of the esophagus are malignant. A very small proportion (under 10%) is [[leiomyoma]] (smooth muscle tumor) or [[gastrointestinal stromal tumor]] (GIST). Malignant tumors are generally [[adenocarcinoma]]s, [[squamous cell carcinoma]]s, and occasionally ''small-cell carcinomas''. The latter share many properties with small-cell [[lung cancer]], and are relatively sensitive to chemotherapy compared to the other types.
Atypical squamous cells with invasion through the basement membrane:
*Cytology:
:*Nucleus - typical central
:*+/-Mitoses.
:*Cytoplasm - "dense-appearing", typically eosinophilic (may be intensely eosinophilic).


+/-Squamous whorls.
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 14:20, 4 September 2015

Esophageal cancer Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Pathophysiology

Microscopic pathology

Atypical squamous cells with invasion through the basement membrane:

  • Cytology:
  • Nucleus - typical central
  • +/-Mitoses.
  • Cytoplasm - "dense-appearing", typically eosinophilic (may be intensely eosinophilic).

+/-Squamous whorls.

References


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