Escherichia coli infection medical therapy: Difference between revisions

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==Overview==
==Overview==
The mainstay of therapy for infections caused by Escherichia coli is antimicrobial therapy.
Antimicrobial therapy is the mainstay of therapy for infections caused by ''Escherichia coli''.


==Medical Therapy==
==Medical Therapy==

Latest revision as of 13:34, 20 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Antimicrobial therapy is the mainstay of therapy for infections caused by Escherichia coli.

Medical Therapy

Antimicrobial therapy

  • Escherichia coli[1]
  • 1. Meningitits
  • 2. Uncomplicated urinary tract infection[2]
  • Preferred agents (IDSA/AUA Guidelines): TMP-SMX DS PO bid for 3 days
  • Alternative regimen (1): Ciprofloxacin 250 mg PO bid
  • Alternative regimen (2): Ciprofloxacin 500 mg XR qd for 3 days
  • Alternative regimen (3): Levofloxacin 250 mg PO qd for 3 days.
  • Alternative regimen (4): Nitrofurantoin 100 mg PO q6h
  • Alternative regimen (5): Nitrofurantoin macrocrystals 100 mg PO bid for 7 days
  • Alternative regimen (6): Fosfomycin 3 g sachet PO single dose
  • Note: For older patients, those with comorbidities (e.g., diabetes mellitus) use 7-10 days course.
  • 3. Pyelonephritis
  • 3.1 Acute uncomplicated pyelonephritis[3]
  • 3.2 Acute pyelonephritis (Hospitalized)[4]
  • 4. Traveler’s diarrhea[5]
  • 4.1 Prophylaxis
  • 4.2 Symptomatic treatment
  • Preferred regimen (1): Bismuth subsalicylate 1 oz PO every 30 min for 8 doses
  • Preferred regimen (2): Loperamide 4 mg PO then 2 mg after each loose stool not to exceed 16 mg daily
  • 4.3 Antibiotic treatment
  • 5. Malacoplakia[6]
  • 6. Bacteremia/pneumonia[7]

References

  1. Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.
  2. Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.
  3. Gilbert, David (2015). The Sanford guide to antimicrobial therapy. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808843.
  4. Gilbert, David (2015). The Sanford guide to antimicrobial therapy. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808843.
  5. "The Practice of Travel Medicine: Guidelines by the Infectious Diseases Society of America" (PDF).
  6. Gilbert, David (2015). The Sanford guide to antimicrobial therapy. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808843.
  7. Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.