Epidural abscess causes

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Epidural abscess Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Epidural abscess from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

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Laboratory Findings

CT

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2] Ogheneochuko Ajari, MB.BS, MS [3]

Overview

Common causes of intracranial epidural abscess include paranasal sinusitis, osteomyelitis of the skull, extension of infection from otitis, mastoiditis or orbit, and direct inoculation during a surgical procedure or trauma. Common causes of spinal epidural abscess include spinal instrumentation, vascular access and IV drug use.

Causes

Life Threatening Causes

Life-threatening conditions may result in death or permanent disability within 24 hours if left untreated. Epidural abscess is a life-threatening condition and must be treated as such irrespective of the cause.

Common Causes

Staphylococcus aureus is responsible for almost two thirds of the reported cases. [1][2] Due to the generalized use of antibiotics through the years, the number of reported cases of SEA due to MRSA has increased exponentially, reaching up to 40% of the cases in some institutions, particularly in patients with spinal or vascular implanted devices. [1] Other less common, but still important organisms are: [1][3][4][5][6][7]

Intracranial Epidural Abscess

Spinal Epidural Abscess

References

  1. 1.0 1.1 1.2 Darouiche, Rabih O. (2006). "Spinal Epidural Abscess". New England Journal of Medicine. 355 (19): 2012–2020. doi:10.1056/NEJMra055111. ISSN 0028-4793.
  2. Rigamonti D, Liem L, Sampath P, Knoller N, Namaguchi Y, Schreibman DL; et al. (1999). "Spinal epidural abscess: contemporary trends in etiology, evaluation, and management". Surg Neurol. 52 (2): 189–96, discussion 197. PMID 10447289.
  3. Pereira CE, Lynch JC (2005). "Spinal epidural abscess: an analysis of 24 cases". Surg Neurol. 63 Suppl 1: S26–9. doi:10.1016/j.surneu.2004.09.021. PMID 15629340.
  4. Danner, R. L.; Hartman, B. J. (1987). "Update of Spinal Epidural Abscess: 35 Cases and Review of the Literature". Clinical Infectious Diseases. 9 (2): 265–274. doi:10.1093/clinids/9.2.265. ISSN 1058-4838.
  5. Nussbaum ES, Rigamonti D, Standiford H, Numaguchi Y, Wolf AL, Robinson WL (1992). "Spinal epidural abscess: a report of 40 cases and review". Surg Neurol. 38 (3): 225–31. PMID 1359657.
  6. Darouiche RO, Hamill RJ, Greenberg SB, Weathers SW, Musher DM (1992). "Bacterial spinal epidural abscess. Review of 43 cases and literature survey". Medicine (Baltimore). 71 (6): 369–85. PMID 1359381.
  7. Longo, Dan L. (Dan Louis) (2012). Harrison's principles of internal medici. New York: McGraw-Hill. ISBN 978-0-07-174889-6.
  8. Griffiths DL (1980). "Tuberculosis of the spine: a review". Adv Tuberc Res. 20: 92–110. PMID 7395641.

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