Cyanosis overview: Difference between revisions
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== Overview == | == Overview == | ||
Cyanosis | [[Cyanosis]] is the condition that there is inadequate [[oxygen]] delivery to peripheral tissue. [[Oxygen]] in the blood is carried in two physical states. Approximately 2% is dissolved in plasma and the other 98% bound to hemoglobin. In [[central cyanosis]] there is increased level of deoxyhemoglobin around 3-5 g/dl. It also could be related to an increased oxygen extraction by the [[peripheral tissues]].<ref name="urlCyanosis - StatPearls - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK482247/ |title=Cyanosis - StatPearls - NCBI Bookshelf |format= |work= |accessdate=}}</ref> An important concept is that cyanosis is dependent upon the absolute concentration of reduced hemoglobin, rather than on the oxygen saturation or the ratio of reduced hemoglobin to oxyhemoglobin Typically, when the level of deoxygenated hemoglobin is around 3 to 5 g/dL, cyanosis becomes very evident.<ref name="pmid19727322">{{cite journal |vauthors=Steinhorn RH |title=Evaluation and management of the cyanotic neonate |journal=Clin Pediatr Emerg Med |volume=9 |issue=3 |pages=169–175 |date=September 2008 |pmid=19727322 |pmc=2598396 |doi=10.1016/j.cpem.2008.06.006 |url=}}</ref> Several factors can affect the appearance of cyanosis includes skin pigmentation, Hemoglobin (Hb) levels, oxygen affinity to the hemoglobin (Hb). | ||
Revision as of 07:57, 21 October 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2]
Overview
Cyanosis is the condition that there is inadequate oxygen delivery to peripheral tissue. Oxygen in the blood is carried in two physical states. Approximately 2% is dissolved in plasma and the other 98% bound to hemoglobin. In central cyanosis there is increased level of deoxyhemoglobin around 3-5 g/dl. It also could be related to an increased oxygen extraction by the peripheral tissues.[1] An important concept is that cyanosis is dependent upon the absolute concentration of reduced hemoglobin, rather than on the oxygen saturation or the ratio of reduced hemoglobin to oxyhemoglobin Typically, when the level of deoxygenated hemoglobin is around 3 to 5 g/dL, cyanosis becomes very evident.[2] Several factors can affect the appearance of cyanosis includes skin pigmentation, Hemoglobin (Hb) levels, oxygen affinity to the hemoglobin (Hb).
References
- ↑ "Cyanosis - StatPearls - NCBI Bookshelf".
- ↑ Steinhorn RH (September 2008). "Evaluation and management of the cyanotic neonate". Clin Pediatr Emerg Med. 9 (3): 169–175. doi:10.1016/j.cpem.2008.06.006. PMC 2598396. PMID 19727322.