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{{Chronic renal failure}}
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==Overview==
The incidence and prevalence of chronic renal failure varies enormously depending on the level of affluence of the country. Developed countries have a higher incident rate of treated end-stage renal failure, whereas the emerging countries have very low incident rates. There are currently about one million patients undergoing [[dialysis]] worldwide, with an incidence of 0.25 million patients each year.
==Epidemiology of CKD in United States==
In 2003, the Third National Health Survey reported a prevalence of CKD in the general population (age 20 or older) of 11% (19.2 million). When divided by CKD stage, 3.3% of participants had stage 1, 3.0% had stage 2, 4.3% had stage 3, 0.2% had stage 4, and 0.2% had stage 5, or ESRD. <ref name="pmid12500213">{{cite journal| author=Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS| title=Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. | journal=Am J Kidney Dis | year= 2003 | volume= 41 | issue= 1 | pages= 1-12 |pmid=12500213 | doi=10.1053/ajkd.2003.50007 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12500213 }} </ref> The study also showed that beyond the classical risk factors notably diabetes and hypertension, age was a separate correlate with CKD prevalence with 11% of people older than 65 years of age having stage 3 or worse CKD in the absence of both diabetes and hypertension. Overall, 26% of the general population above 65 years of age has some form of kidney disease manifested by an eGFR <60 mL/min/1.73 m<sup>2</sup>. Ethnicity was found to be related to CKD and ESRD prevalence. ESRD was slightly more prevalent in non-Hispanic blacks than in non-Hispanic whites. In contrast, less severe stages of CKD were more common among whites, and least common among Mexican Americans.<ref name="pmid12500213">{{cite journal| author=Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS| title=Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. | journal=Am J Kidney Dis | year= 2003 | volume= 41 | issue= 1 | pages= 1-12 |pmid=12500213| doi=10.1053/ajkd.2003.50007 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12500213 }}
==References==
{{Reflist}}

Revision as of 17:08, 31 October 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]

Overview

The incidence and prevalence of chronic renal failure varies enormously depending on the level of affluence of the country. Developed countries have a higher incident rate of treated end-stage renal failure, whereas the emerging countries have very low incident rates. There are currently about one million patients undergoing dialysis worldwide, with an incidence of 0.25 million patients each year.

Epidemiology of CKD in United States

In 2003, the Third National Health Survey reported a prevalence of CKD in the general population (age 20 or older) of 11% (19.2 million). When divided by CKD stage, 3.3% of participants had stage 1, 3.0% had stage 2, 4.3% had stage 3, 0.2% had stage 4, and 0.2% had stage 5, or ESRD. [1] The study also showed that beyond the classical risk factors notably diabetes and hypertension, age was a separate correlate with CKD prevalence with 11% of people older than 65 years of age having stage 3 or worse CKD in the absence of both diabetes and hypertension. Overall, 26% of the general population above 65 years of age has some form of kidney disease manifested by an eGFR <60 mL/min/1.73 m2. Ethnicity was found to be related to CKD and ESRD prevalence. ESRD was slightly more prevalent in non-Hispanic blacks than in non-Hispanic whites. In contrast, less severe stages of CKD were more common among whites, and least common among Mexican Americans.<ref name="pmid12500213">Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS (2003). "Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey". Am J Kidney Dis. 41 (1): 1–12. doi:10.1053/ajkd.2003.50007. PMID 12500213.

References

  1. Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS (2003). "Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey". Am J Kidney Dis. 41 (1): 1–12. doi:10.1053/ajkd.2003.50007. PMID 12500213.