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**Presence of bone marrow [[edema]] frequently seen surrounding chondroblastomas is helpful, as it is not a usual feature of chondromyxoid [[fibroma]]s, [[giant cell]] tumors, or enchondromas.<ref name="vd">Chondroblastoma. Radiopedia. http://radiopaedia.org/articles/chondroblastoma Accessed on December 21, 2015.</ref><ref name="pmid11687691">{{cite journal| author=Erickson JK, Rosenthal DI, Zaleske DJ, Gebhardt MC, Cates JM| title=Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases. | journal=Radiology | year= 2001 | volume= 221 | issue= 2 | pages= 463-8 | pmid=11687691 | doi=10.1148/radiol.2212010262 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11687691  }} </ref>
**Presence of bone marrow [[edema]] frequently seen surrounding chondroblastomas is helpful, as it is not a usual feature of chondromyxoid [[fibroma]]s, [[giant cell]] tumors, or enchondromas.<ref name="vd">Chondroblastoma. Radiopedia. http://radiopaedia.org/articles/chondroblastoma Accessed on December 21, 2015.</ref><ref name="pmid11687691">{{cite journal| author=Erickson JK, Rosenthal DI, Zaleske DJ, Gebhardt MC, Cates JM| title=Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases. | journal=Radiology | year= 2001 | volume= 221 | issue= 2 | pages= 463-8 | pmid=11687691 | doi=10.1148/radiol.2212010262 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11687691  }} </ref>
*'''Fibrocartilaginous [[dysplasia]]'''
*'''Fibrocartilaginous [[dysplasia]]'''
**Fibrous [[dysplasia]] with an extensive cartilagenous differentiation resulting in a picture that mimics enchondroma. Cellular [[atypia]] in the surrounding [[stroma]] in fibrocartilagenous [[dysplasia]] helps in the differentiation.<ref name="pmid16329546">{{cite journal| author=Muezzinoglu B, Oztop F| title=Fibrocartilaginous dysplasia: a variant of fibrous dysplasia. | journal=Malays J Pathol | year= 2001 | volume= 23 | issue= 1 | pages= 35-9 | pmid=16329546 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16329546  }} </ref>  
**Fibrous [[dysplasia]] is seen with an extensive cartilagenous differentiation that results in a picture that mimics enchondroma.  
**Cellular [[atypia]] in the surrounding [[stroma]] helps in the differentiation.<ref name="pmid16329546">{{cite journal| author=Muezzinoglu B, Oztop F| title=Fibrocartilaginous dysplasia: a variant of fibrous dysplasia. | journal=Malays J Pathol | year= 2001 | volume= 23 | issue= 1 | pages= 35-9 | pmid=16329546 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16329546  }} </ref>  
*[[Bone island|'''Bone islands''']]<ref name="hh">Enostosis. Radiopedia. http://radiopaedia.org/articles/enostosis Accessed on December 18, 2015.</ref>
*[[Bone island|'''Bone islands''']]<ref name="hh">Enostosis. Radiopedia. http://radiopaedia.org/articles/enostosis Accessed on December 18, 2015.</ref>
**Small focus of [[compact bone]] within the [[cancellous bone]].
**Small focus of [[compact bone]] within the [[cancellous bone]]
**There is no cortical destruction or involvement of the surrounding [[soft tissue]]s.
**No cortical destruction or involvement of the surrounding [[soft tissue]]s
*[[Bone infarct|'''Bone infarcts''']]
*[[Bone infarct|'''Bone infarcts''']]
**Differentiating an enchondroma from a bone infarct on plain film may be difficult. An enchondroma usually causes endosteal scalloping while an [[infarct]] will not. An infarct usually has a well-defined, sclerotic serpentine border, while an enchondroma does not.<ref name="en">Enchondroma. Wikipedia. https://en.wikipedia.org/wiki/Enchondroma Accessed on December 18, 2015.</ref>
**Differentiating an enchondroma from a bone infarct on plain film may be difficult.  
**An enchondroma usually causes endosteal scalloping while an [[infarct]] will not.  
**An infarct usually has a well-defined, sclerotic serpentine border, while an enchondroma does not.<ref name="en">Enchondroma. Wikipedia. https://en.wikipedia.org/wiki/Enchondroma Accessed on December 18, 2015.</ref>
Periosteal chondroma must be differentiated from the following:
Periosteal chondroma must be differentiated from the following:
*Periosteal [[chondrosarcoma]]
*Periosteal [[chondrosarcoma]]

Revision as of 19:00, 11 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

Enchondroma must be differentiated from low-grade chondrosarcoma, fibrocartilaginous dysplasia, bone islands and bone infarcts.[1][2][3][4][5] Periosteal chondroma must be differentiated from periosteal chondrosarcoma and periosteal osteosarcoma.

Differential Diagnosis

Enchondroma must be differentiated from the following:

  • Low-grade chondrosarcoma
    • When differentiating an enchondroma from a chondrosarcoma, the radiographic image may be equivocal. However, periostitis is not usually seen with an uncomplicated enchondroma.[1]
  • Chondroblastoma
    • Presence of bone marrow edema frequently seen surrounding chondroblastomas is helpful, as it is not a usual feature of chondromyxoid fibromas, giant cell tumors, or enchondromas.[2][3]
  • Fibrocartilaginous dysplasia
    • Fibrous dysplasia is seen with an extensive cartilagenous differentiation that results in a picture that mimics enchondroma.
    • Cellular atypia in the surrounding stroma helps in the differentiation.[4]
  • Bone islands[5]
  • Bone infarcts
    • Differentiating an enchondroma from a bone infarct on plain film may be difficult.
    • An enchondroma usually causes endosteal scalloping while an infarct will not.
    • An infarct usually has a well-defined, sclerotic serpentine border, while an enchondroma does not.[1]

Periosteal chondroma must be differentiated from the following:

References

  1. 1.0 1.1 1.2 Enchondroma. Wikipedia. https://en.wikipedia.org/wiki/Enchondroma Accessed on December 18, 2015.
  2. 2.0 2.1 Chondroblastoma. Radiopedia. http://radiopaedia.org/articles/chondroblastoma Accessed on December 21, 2015.
  3. 3.0 3.1 Erickson JK, Rosenthal DI, Zaleske DJ, Gebhardt MC, Cates JM (2001). "Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases". Radiology. 221 (2): 463–8. doi:10.1148/radiol.2212010262. PMID 11687691.
  4. 4.0 4.1 Muezzinoglu B, Oztop F (2001). "Fibrocartilaginous dysplasia: a variant of fibrous dysplasia". Malays J Pathol. 23 (1): 35–9. PMID 16329546.
  5. 5.0 5.1 Enostosis. Radiopedia. http://radiopaedia.org/articles/enostosis Accessed on December 18, 2015.


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