Chondroma causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2], Soujanya Thummathati, MBBS [3]

Overview

The cause of chondromas has not been identified.

The cause of chondromas has not been identified. Fibroblast growth factor receptor (FGFR3) deletion may be induced multiple chondroma-like lesions, including enchondromas and osteochondromas.^[1]
However, enchondroma is believed to occur either as:
- An overgrowth of the cartilage that lines the ends of the bones
- A persistent growth of original embryonic cartilage.

↑ Zhou S, Xie Y, Tang J, Huang J, Huang Q, Xu W, Wang Z, Luo F, Wang Q, Chen H, Du X, Shen Y, Chen D, Chen L (June 2015). "FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling". PLoS Genet. 11 (6): e1005214. doi:10.1371/journal.pgen.1005214. PMC 4474636. PMID 26091072.