Difference between revisions of "Cardiac amyloidosis electrocardiogram"

Jump to: navigation, search
Line 10: Line 10:
* [[Low voltage complexes]]
* [[Low voltage complexes]]
* [[Pseudo-infarct pattern]] of [[poor R wave progression]]
* [[Pseudo-infarct pattern]] of [[poor R wave progression]]
* [[Left ventricular hypertrophy]] pattern
* [[Left ventricular hypertrophy on electrocardiogram]]
* Higher degree [[AV block]]s
* Higher degree [[AV block]]s
* [[Bundle branch block]]s: [[Left bundle branch block]] is seen in 40% of the patients with [[wild-type ATTR]] versus 4% of those with [[AL amyloid type]].
* [[Bundle branch block]]s: [[Left bundle branch block]] is seen in 40% of the patients with [[wild-type ATTR]] versus 4% of those with [[AL amyloid type]].

Revision as of 21:54, 29 October 2019

Cardiac amyloidosis Microchapters


Patient Information


Historical Perspective




Differentiating Cardiac Amyloidosis from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings



Echocardiography and Ultrasound

CT scan


Other Imaging Findings

Other Diagnostic Studies


Medical Therapy


Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Cardiac amyloidosis electrocardiogram On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides


American Roentgen Ray Society Images of Cardiac amyloidosis electrocardiogram

All Images
Echo & Ultrasound
CT Images

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Cardiac amyloidosis electrocardiogram

CDC onCardiac amyloidosis electrocardiogram

Cardiac amyloidosis electrocardiogram in the news

Blogs on Cardiac amyloidosis electrocardiogram

Directions to Hospitals Treating Cardiac amyloidosis

Risk calculators and risk factors for Cardiac amyloidosis electrocardiogram

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Aarti Narayan, M.B.B.S [3]; Cafer Zorkun, M.D., Ph.D. [4]


The combination of low voltage electrocardiographic pattern and increased thickness of the left ventricular posterior wall and interventricular septum on echocardiogram is highly specific for cardiac amyloidosis. Cardiac conduction and rhythm disturbances are common in cardiac amyloidosis, however, direct infiltration of the specialized conduction tissue of the heart by the amyloid may not account for the majority of these disturbances.


Electrocardiographic findings in cardiac amyloidosis include:[1][2][3]

Lack of variability in the heart rate due to autonomic dysfunction can be found on Holter monitoring. This lack of variability is an important predictor of 1-year mortality in these patients.[4] This lack of variability in the heart rate was shown to be a consistent predictive parameter of short-term mortality in patients with AL type cardiac amyloidosis compared to those with AA type.


  1. Ridolfi RL, Bulkley BH, Hutchins GM (1977). "The conduction system in cardiac amyloidosis. Clinical and pathologic features of 23 patients". The American Journal of Medicine. 62 (5): 677–86. PMID 871125. Unknown parameter |month= ignored (help)
  2. Rahman JE, Helou EF, Gelzer-Bell R; et al. (2004). "Noninvasive diagnosis of biopsy-proven cardiac amyloidosis". Journal of the American College of Cardiology. 43 (3): 410–5. doi:10.1016/j.jacc.2003.08.043. PMID 15013123. Unknown parameter |month= ignored (help)
  3. Murtagh B, Hammill SC, Gertz MA, Kyle RA, Tajik AJ, Grogan M (2005). "Electrocardiographic findings in primary systemic amyloidosis and biopsy-proven cardiac involvement". The American Journal of Cardiology. 95 (4): 535–7. doi:10.1016/j.amjcard.2004.10.028. PMID 15695149. Unknown parameter |month= ignored (help)
  4. Reyners AK, Hazenberg BP, Reitsma WD, Smit AJ (2002). "Heart rate variability as a predictor of mortality in patients with AA and AL amyloidosis". European Heart Journal. 23 (2): 157–61. doi:10.1053/euhj.2001.2972. PMID 11785998. Unknown parameter |month= ignored (help)