Bone or cartilage mass causes: Difference between revisions

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{{CMG}}; {{AE}} {{Ochuko}}
{{Bone or cartilage mass}}
{{CMG}}; {{AE}} {{Ochuko}} {{MV}}


==Overview==
==Overview==
Bone and cartilage tumors may be caused by precursor lesions, such as radiation injury, chronic osteomyelitis, and some genetically determined syndromes (McCune-Albright syndrome, Ollier disease, Maffucci syndrome, and Beckwith-Wiedemann syndrome).<ref name="bone1">Alina Maria Sisu. On the Bone Tumours: Overview, Classification, Incidence, Histopathological Issues, Behavior and Review Using Literature Data. http://www.intechopen.com/books/histopathology-reviews-and-recent-advances/on-the-bone-tumours-overview-classification-incidence-histopathological-issues-behavior-and-review Accessed on February 2, 2016 </ref>


==Causes==
==Causes==
===Common Causes===
*Bone and cartilage tumors may be caused by precursor lesions, such as:<ref name="bone1">Alina Maria Sisu. On the Bone Tumours: Overview, Classification, Incidence, Histopathological Issues, Behavior and Review Using Literature Data. http://www.intechopen.com/books/histopathology-reviews-and-recent-advances/on-the-bone-tumours-overview-classification-incidence-histopathological-issues-behavior-and-review Accessed on February 2, 2016 </ref>
:*[[Radiation injury]]
:*Chronic [[osteomyelitis]]
:*Genetically determined syndromes, such as:
::*[[McCune-Albright syndrome]]
::*[[Ollier disease]]
::*[[Maffucci syndrome]]
::*[[Beckwith-Wiedemann syndrome]]
===Causes by Organ System===


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| '''Dental'''
| '''Dental'''
|bgcolor="Beige"| [[Gardner's syndrome]], [[simple bone cyst]]
|bgcolor="Beige"| [[Gardner's syndrome]], [[Simple bone cyst]]
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| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"|[[Carcinoid syndrome]], [[thyroid carcinoma]]
|bgcolor="Beige"|[[Carcinoid syndrome]], [[Thyroid carcinoma]]
|-
|-
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| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[Congenital generalized lipodystrophy]], [[fibrous dysplasia]], [[Gardner's syndrome]], [[Nasu-Hakola disease]], [[osteopoikilosis]], [[Rosai-Dorfman disease]]
|bgcolor="Beige"| [[Congenital generalized lipodystrophy]], [[Fibrous dysplasia]], [[Gardner's syndrome]], [[Nasu-Hakola disease]], [[Osteopoikilosis]], [[Rosai-Dorfman disease]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| [[Erdheim-Chester disease]], [[histiocytosis X]], [[langerhans cell histiocytosis]], [[multiple myeloma]], [[plasma cell myeloma]], [[plasmacytoma|solitary plasmacytoma of bone]]
|bgcolor="Beige"| [[Erdheim-Chester disease]], [[Histiocytosis X]], [[Langerhans cell histiocytosis]], [[Multiple myeloma]], [[Plasma cell myeloma]], [[plasmacytoma|Solitary plasmacytoma of bone]]
|-
|-
|-bgcolor="LightSteelBlue"
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| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| [[abscess|Bone abscess]], [[eumycetoma]], [[osteomyelitis]]
|bgcolor="Beige"| [[abscess|Bone abscess]], [[Eumycetoma]], [[Osteomyelitis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| [[Adamantinoma]], [[aneurysmal bone cyst]], [[abscess|bone abscess]], [[bone cancer]], [[bone cyst]], [[bone spur]], [[chondroblastoma]], [[fibroma classification|desmoplastic fibroma of bone]], [[enchondroma]], [[Erdheim-Chester disease]], [[Ewing's sarcoma]], [[fibrous dysplasia]], [[giant cell tumor of bone]], [[intraosseous lipoma]], [[Nasu-Hakola disease]], [[Osgood-Schlatter disease]], [[osteitis fibrosa cystica]], [[osteoblastoma]], [[osteochondroma]], [[osteochondromyxoma]], [[osteoclastoma]], [[osteofibrous dysplasia]], [[osteoma classification|osteoid osteoma]], [[osteoma]], [[osteopoikilosis]], [[osteosarcoma]], [[Paget's disease of bone]], [[parosteal osteosarcoma]], [[periosteal osteosarcoma]], [[primary lymphoma of the bone]], [[primary lymphoma of the bone|primary non-Hodgkin lymphoma of bone]], [[simple bone cyst]], [[small cell osteosarcoma]], [[synovial chondromatosis]], [[telangiectatic osteosarcoma]], [[simple bone cyst|unicameral bone cyst]]
|bgcolor="Beige"| [[Adamantinoma]], [[Aneurysmal bone cyst]], [[Bone abscess]], [[Bone cancer]], [[Bone cyst]], [[Bone spur]], [[Chondroblastoma]], [[fibroma classification|Desmoplastic fibroma of bone]], [[Enchondroma]], [[Erdheim-Chester disease]], [[Ewing's sarcoma]], [[Fibrous dysplasia]], [[Giant cell tumor of bone]], [[Intraosseous lipoma]], [[Nasu-Hakola disease]], [[Osgood-Schlatter disease]], [[Osteitis fibrosa cystica]], [[Osteoblastoma]], [[Osteochondroma]], [[Osteochondromyxoma]], [[Osteoclastoma]], [[Osteofibrous dysplasia]], [[osteoma classification|Osteoid osteoma]], [[Osteoma]], [[Osteopoikilosis]], [[Osteosarcoma]], [[Paget's disease of bone]], [[Parosteal osteosarcoma]], [[Periosteal osteosarcoma]], [[Primary lymphoma of the bone]], [[primary lymphoma of the bone|Primary non-Hodgkin lymphoma of bone]], [[Simple bone cyst]], [[Small cell osteosarcoma]], [[Synovial chondromatosis]], [[Telangiectatic osteosarcoma]], [[simple bone cyst|Unicameral bone cyst]]
|-
|-
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| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| '''Benign:''' [[Benign notochordal cell tumor]], [[chondroblastoma]], [[harmatoma|chondromesenchymal hamartoma]], [[fibroma classification|chondromyxoid fibroma]], [[fibroma classification|desmoplastic fibroma of bone]], [[enchondroma]], [[hemangioendothelioma|epithelioid hemangioendothelioma]], [[epithelioid hemangioma]], [[hemangioma]], [[hemangiopericytoma]], [[histiocytosis X]], [[langerhans cell histiocytosis]], [[nonossifying fibroma]], [[fibroma classification|ossifying fibroma]], [[osteitis fibrosa cystica]], [[osteoblastoma]],  [[osteochondroma]], [[osteochondromyxoma]], [[osteoma classification|osteoid osteoma]], [[osteoma]], [[Paget's disease of bone]], [[chondroma classification|periosteal chondroma]],
|bgcolor="Beige"| '''Benign:''' [[Benign notochordal cell tumor]], [[Chondroblastoma]], [[harmatoma|Chondromesenchymal hamartoma]], [[fibroma classification|Chondromyxoid fibroma]], [[Cortical desmoid]], [[fibroma classification|Desmoplastic fibroma of bone]], [[Enchondroma]], [[hemangioendothelioma|Epithelioid hemangioendothelioma]], [[Epithelioid hemangioma]], [[Hemangioma]], [[Hemangiopericytoma]], [[Histiocytosis X]], [[Langerhans cell histiocytosis]], [[Nonossifying fibroma]], [[fibroma classification|Ossifying fibroma]], [[Osteitis fibrosa cystica]], [[Osteoblastoma]],  [[Osteochondroma]], [[Osteochondromyxoma]], [[osteoma classification|Osteoid osteoma]], [[Osteoma]], [[Paget's disease of bone]], [[chondroma classification|Periosteal chondroma]]


'''Malignant:''' [[Adamantinoma]], [[angiosarcoma]], [[bladder cancer]], [[bone cancer]], [[breast cancer]], [[bronchogenic carcinoma]], [[carcinoid syndrome]], [[chondrosarcoma]], [[chordoma]], [[chondrosarcoma|clear cell chondrosarcoma]], [[chondrosarcoma|dedifferentiated chondrosarcoma]], [[hemangioendothelioma|epithelioid hemangioendothelioma]], [[Ewing's sarcoma]], [[fibrosarcoma]], [[giant cell tumor of bone]], [[hemangiopericytoma]], [[lymphoma]], [[malignant fibrous histiocytoma]], [[melanoma]], [[chondrosarcoma|mesenchymal chondrosarcoma]], [[multiple myeloma]], [[osteoclastoma]], [[osteosarcoma]],  [[parosteal osteosarcoma]], [[plasma cell myeloma]], [[periosteal osteosarcoma]],  [[primary lymphoma of the bone]], [[primary lymphoma of the bone|primary non-Hodgkin lymphoma of bone]],  [[prostate cancer]], [[small cell osteosarcoma]],  [[plasmacytoma|solitary plasmacytoma of bone]], [[rhabdomyosarcoma]], [[telangiectatic osteosarcoma]], [[thyroid carcinoma]],
'''Malignant:''' [[Adamantinoma]], [[Angiosarcoma]], [[Bladder cancer]], [[Bone cancer]], [[Breast cancer]], [[Bronchogenic carcinoma]], [[Carcinoid syndrome]], [[Chondrosarcoma]], [[Chordoma]], [[chondrosarcoma|Clear cell chondrosarcoma]], [[chondrosarcoma|Dedifferentiated chondrosarcoma]], [[hemangioendothelioma|Epithelioid hemangioendothelioma]], [[Ewing's sarcoma]], [[Fibrosarcoma]], [[Giant cell tumor of bone]], [[Hemangiopericytoma]], [[Lymphoma]], [[Malignant fibrous histiocytoma]], [[Melanoma]], [[chondrosarcoma|Mesenchymal chondrosarcoma]], [[Multiple myeloma]], [[Osteoclastoma]], [[Osteosarcoma]],  [[Parosteal osteosarcoma]], [[Plasma cell myeloma]], [[Periosteal osteosarcoma]],  [[Primary lymphoma of the bone]], [[primary lymphoma of the bone|Primary non-Hodgkin lymphoma of bone]],  [[Prostate cancer]], [[Small cell osteosarcoma]],  [[plasmacytoma|Solitary plasmacytoma of bone]], [[Rhabdomyosarcoma]], [[Telangiectatic osteosarcoma]], [[Thyroid carcinoma]]


'''Metastatic:''' [[Bladder cancer]], [[bone cancer]], [[breast cancer]], [[bronchogenic carcinoma]], [[carcinoid syndrome]], [[chondrosarcoma]], [[chondrosarcoma|clear cell chondrosarcoma]], [[chondrosarcoma|dedifferentiated chondrosarcoma]], [[Ewing's sarcoma]], [[fibrosarcoma]], [[giant cell tumor of bone]], [[melanoma]], [[chondrosarcoma|mesenchymal chondrosarcoma]], [[osteoclastoma]], [[osteosarcoma]], [[periosteal osteosarcoma]], [[prostate cancer]], [[rhabdomyosarcoma]], [[telangiectatic osteosarcoma]], [[thyroid carcinoma]]
'''Metastatic:''' [[Bladder cancer]], [[Bone cancer]], [[Breast cancer]], [[Bronchogenic carcinoma]], [[Carcinoid syndrome]], [[Chondrosarcoma]], [[chondrosarcoma|lCear cell chondrosarcoma]], [[chondrosarcoma|Dedifferentiated chondrosarcoma]], [[Ewing's sarcoma]], [[Fibrosarcoma]], [[Giant cell tumor of bone]], [[Melanoma]], [[chondrosarcoma|Mesenchymal chondrosarcoma]], [[Osteoclastoma]], [[Osteosarcoma]], [[Periosteal osteosarcoma]], [[Prostate cancer]], [[Rhabdomyosarcoma]], [[Telangiectatic osteosarcoma]], [[Thyroid carcinoma]]
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| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| [[Bronchogenic carcinoma]], [[sarcoidosis]]
|bgcolor="Beige"| [[Bronchogenic carcinoma]], [[Sarcoidosis]]
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|-
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| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Cortical desmoid]]
|-
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==References==
 
{{Reflist|2}}
 
[[Category:Up-To-Date]]
 
[[Category:Oncology]]
 
[[Category:Medicine]]
 
[[Category:Rheumatology]]
 
[[Category:Orthopedics]]
 
 
*[[Osteomyelitis]]
*[[Giant cell tumor of bone|Giant cell tumors]]
*[[Ewing's sarcoma]]
*[[Malignant fibrous histiocytoma]]  
*[[Lymphoma]]
*[[Osteoblastoma]]  
*[[Aneurysmal bone cyst]]
*[[Rhabdomyosarcoma]]
*[[Fibrosarcoma]]
*Cortical desmoid

Latest revision as of 02:31, 6 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogheneochuko Ajari, MB.BS, MS [2] Maria Fernanda Villarreal, M.D. [3]

Overview

Bone and cartilage tumors may be caused by precursor lesions, such as radiation injury, chronic osteomyelitis, and some genetically determined syndromes (McCune-Albright syndrome, Ollier disease, Maffucci syndrome, and Beckwith-Wiedemann syndrome).[1]

Causes

Common Causes

  • Bone and cartilage tumors may be caused by precursor lesions, such as:[1]


Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning No underlying causes
Dental Gardner's syndrome, Simple bone cyst
Dermatologic Melanoma
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine Carcinoid syndrome, Thyroid carcinoma
Environmental No underlying causes
Gastroenterologic Carcinoid syndrome
Genetic Congenital generalized lipodystrophy, Fibrous dysplasia, Gardner's syndrome, Nasu-Hakola disease, Osteopoikilosis, Rosai-Dorfman disease
Hematologic Erdheim-Chester disease, Histiocytosis X, Langerhans cell histiocytosis, Multiple myeloma, Plasma cell myeloma, Solitary plasmacytoma of bone
Iatrogenic No underlying causes
Infectious Disease Bone abscess, Eumycetoma, Osteomyelitis
Musculoskeletal/Orthopedic Adamantinoma, Aneurysmal bone cyst, Bone abscess, Bone cancer, Bone cyst, Bone spur, Chondroblastoma, Desmoplastic fibroma of bone, Enchondroma, Erdheim-Chester disease, Ewing's sarcoma, Fibrous dysplasia, Giant cell tumor of bone, Intraosseous lipoma, Nasu-Hakola disease, Osgood-Schlatter disease, Osteitis fibrosa cystica, Osteoblastoma, Osteochondroma, Osteochondromyxoma, Osteoclastoma, Osteofibrous dysplasia, Osteoid osteoma, Osteoma, Osteopoikilosis, Osteosarcoma, Paget's disease of bone, Parosteal osteosarcoma, Periosteal osteosarcoma, Primary lymphoma of the bone, Primary non-Hodgkin lymphoma of bone, Simple bone cyst, Small cell osteosarcoma, Synovial chondromatosis, Telangiectatic osteosarcoma, Unicameral bone cyst
Neurologic Benign notochordal cell tumor, Nasu-Hakola disease
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Benign: Benign notochordal cell tumor, Chondroblastoma, Chondromesenchymal hamartoma, Chondromyxoid fibroma, Cortical desmoid, Desmoplastic fibroma of bone, Enchondroma, Epithelioid hemangioendothelioma, Epithelioid hemangioma, Hemangioma, Hemangiopericytoma, Histiocytosis X, Langerhans cell histiocytosis, Nonossifying fibroma, Ossifying fibroma, Osteitis fibrosa cystica, Osteoblastoma, Osteochondroma, Osteochondromyxoma, Osteoid osteoma, Osteoma, Paget's disease of bone, Periosteal chondroma

Malignant: Adamantinoma, Angiosarcoma, Bladder cancer, Bone cancer, Breast cancer, Bronchogenic carcinoma, Carcinoid syndrome, Chondrosarcoma, Chordoma, Clear cell chondrosarcoma, Dedifferentiated chondrosarcoma, Epithelioid hemangioendothelioma, Ewing's sarcoma, Fibrosarcoma, Giant cell tumor of bone, Hemangiopericytoma, Lymphoma, Malignant fibrous histiocytoma, Melanoma, Mesenchymal chondrosarcoma, Multiple myeloma, Osteoclastoma, Osteosarcoma, Parosteal osteosarcoma, Plasma cell myeloma, Periosteal osteosarcoma, Primary lymphoma of the bone, Primary non-Hodgkin lymphoma of bone, Prostate cancer, Small cell osteosarcoma, Solitary plasmacytoma of bone, Rhabdomyosarcoma, Telangiectatic osteosarcoma, Thyroid carcinoma

Metastatic: Bladder cancer, Bone cancer, Breast cancer, Bronchogenic carcinoma, Carcinoid syndrome, Chondrosarcoma, lCear cell chondrosarcoma, Dedifferentiated chondrosarcoma, Ewing's sarcoma, Fibrosarcoma, Giant cell tumor of bone, Melanoma, Mesenchymal chondrosarcoma, Osteoclastoma, Osteosarcoma, Periosteal osteosarcoma, Prostate cancer, Rhabdomyosarcoma, Telangiectatic osteosarcoma, Thyroid carcinoma

Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Bronchogenic carcinoma, Sarcoidosis
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma Cortical desmoid
Urologic No underlying causes
Miscellaneous No underlying causes

References

  1. ↑ 1.0 1.1 Alina Maria Sisu. On the Bone Tumours: Overview, Classification, Incidence, Histopathological Issues, Behavior and Review Using Literature Data. http://www.intechopen.com/books/histopathology-reviews-and-recent-advances/on-the-bone-tumours-overview-classification-incidence-histopathological-issues-behavior-and-review Accessed on February 2, 2016
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