Boil pathophysiology: Difference between revisions
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Furuncle is a localized, deep, [[suppurative]], [[necrotizing]] form of [[folliculitis]] which involves [[dermis]] and [[subcutaneous tissue]]. ''[[Staphylococcus aureus]]'' is the most common causative agent. Following [[abrasion]] or cut the [[pathogen]] uses the entry site to invade and colonize the [[hair follicle]] leading to the formation of tender, red, perifollicular nodule. It later becomes painful and fluctuant terminating in the discharge of [[pus]] and [[necrotic]] plug which may leave a [[scar]].<ref name="pmid24591845">{{cite journal| author=Ibler KS, Kromann CB| title=Recurrent furunculosis - challenges and management: a review. | journal=Clin Cosmet Investig Dermatol | year= 2014 | volume= 7 | issue= | pages= 59-64 | pmid=24591845 | doi=10.2147/CCID.S35302 | pmc=3934592 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24591845 }} </ref> | Furuncle is a localized, deep, [[suppurative]], [[necrotizing]] form of [[folliculitis]] which involves [[dermis]] and [[subcutaneous tissue]]. ''[[Staphylococcus aureus]]'' is the most common causative agent. Following [[abrasion]] or cut the [[pathogen]] uses the entry site to invade and colonize the [[hair follicle]] leading to the formation of tender, red, perifollicular nodule. It later becomes painful and fluctuant terminating in the discharge of [[pus]] and [[necrotic]] plug which may leave a [[scar]].<ref name="pmid24591845">{{cite journal| author=Ibler KS, Kromann CB| title=Recurrent furunculosis - challenges and management: a review. | journal=Clin Cosmet Investig Dermatol | year= 2014 | volume= 7 | issue= | pages= 59-64 | pmid=24591845 | doi=10.2147/CCID.S35302 | pmc=3934592 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24591845 }} </ref> | ||
Revision as of 18:53, 8 August 2016
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Boil Microchapters |
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Boil pathophysiology On the Web |
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American Roentgen Ray Society Images of Boil pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Boil (furuncle) is the tender, deep, dome shaped skin infection of the hair follicle.
Pathogenesis
Furuncle is a localized, deep, suppurative, necrotizing form of folliculitis which involves dermis and subcutaneous tissue. Staphylococcus aureus is the most common causative agent. Following abrasion or cut the pathogen uses the entry site to invade and colonize the hair follicle leading to the formation of tender, red, perifollicular nodule. It later becomes painful and fluctuant terminating in the discharge of pus and necrotic plug which may leave a scar.[1]
Furunculosis is the acute or chronic appearance of a number of furuncles at multiple skin sites. Recurrent furunculosis is defined as three or more attacks within 12 month period.[1] It is a contagious condition which usually develops in moist or sweaty areas such as the scalp, face, buttocks, axillae and areas which are subject to friction and perspiration.
Group of furuncles coalesce to form carbuncle.
Associated Conditions
Gross Pathology
On gross pathology, the following are characteristic findings of boil(furuncle):
- It begins as a firm, tender, red, dome shaped nodule
- It later becomes fluctuant (Pus filled) and painful
- They vary in size
Microscopic Pathology
On microscopic histopathological analysis, the following are characteristic findings of boil(furuncle):
- Infiltrate predominantly consists of neutrophils with in the wall and ostia of hair follicle which later becomes more mixed with lymphocytes and macrophages creating a central focus of necrosis.
- Inflammation of hair follicle can either be:
- Superficial(primarily involving the infandibulum)
- Deep
Images
The following is gross image associated with furuncle.
References
- ↑ 1.0 1.1 Ibler KS, Kromann CB (2014). "Recurrent furunculosis - challenges and management: a review". Clin Cosmet Investig Dermatol. 7: 59–64. doi:10.2147/CCID.S35302. PMC 3934592. PMID 24591845.
- ↑ wikipedia. Furuncle (2016) https://en.wikipedia.org/wiki/Boil#/media/File:Furoncle.jpg Accessed on August 8,2016
