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==Overview==
[[Image:Clavulanic acid structure.svg|thumb|left|[[Clavulanic acid]]]]
[[Image:Sulbactam.svg|thumb|left|[[Sulbactam]]]]
[[Image:Tazobactam structure.svg|thumb|left|[[Tazobactam]]]]
A '''beta-lactamase inhibitor''' is a drug given in conjunction with a [[beta-lactam antibiotic]]. Although the inhibitor does not usually have significant antibiotic activity on its own,<ref>{{cite web |url=http://www.fhsu.edu/nursing/otitis/bl_inhibit.html |title=Beta-Lactamase Inhibitors |date=October 2000 |accessdate=2007-08-17 |publisher=Department of Nursing of the [[Fort Hays State University]] College of Health and Life Sciences}}</ref> it still plays an important role by disabling or slowing down the action of [[beta-lactamase]].
A '''beta-lactamase inhibitor''' is a drug given in conjunction with a [[beta-lactam antibiotic]]. Although the inhibitor does not usually have significant antibiotic activity on its own,<ref>{{cite web |url=http://www.fhsu.edu/nursing/otitis/bl_inhibit.html |title=Beta-Lactamase Inhibitors |date=October 2000 |accessdate=2007-08-17 |publisher=Department of Nursing of the [[Fort Hays State University]] College of Health and Life Sciences}}</ref> it still plays an important role by disabling or slowing down the action of [[beta-lactamase]].


Beta-lactamase inhibitors in clinical use include [[clavulanic acid]] and its potassium salt (usually combined with [[amoxicillin]] or [[ticarcillin]]), [[sulbactam]] and [[tazobactam]].
Beta-lactamase inhibitors in clinical use include [[clavulanic acid]] and its potassium salt (usually combined with [[amoxicillin]] or [[ticarcillin]]), [[sulbactam]] and [[tazobactam]].
==References==
==References==
<references/>
{{Reflist|2}}


{{PenicillinAntiBiotics}}
{{PenicillinAntiBiotics}}
[[Category:Beta-lactamase inhibitors]]
[[Category:Beta-lactamase inhibitors]]
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Latest revision as of 22:50, 17 November 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

A beta-lactamase inhibitor is a drug given in conjunction with a beta-lactam antibiotic. Although the inhibitor does not usually have significant antibiotic activity on its own,[1] it still plays an important role by disabling or slowing down the action of beta-lactamase.

Beta-lactamase inhibitors in clinical use include clavulanic acid and its potassium salt (usually combined with amoxicillin or ticarcillin), sulbactam and tazobactam.

References

  1. "Beta-Lactamase Inhibitors". Department of Nursing of the Fort Hays State University College of Health and Life Sciences. October 2000. Retrieved 2007-08-17.