Aortic dissection epidemiology and demographics: Difference between revisions

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{{Template:Aortic dissection}}
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{{CMG}}; '''Associate Editor-In-Chief:''' {{Sahar}} {{CZ}}
{{CMG}}
==Overview==
 
The [[incidence]] of aortic dissection is approximately 6 per 100,000 individuals worldwide.The [[incidence]] of aortic dissection increases with age, with a mean age of 63 years. Men are more commonly affected by aortic dissection than women. However, the [[prognosis]] tends to be worse in women due to unusual presentations. There is no [[racial]] predilection to aortic dissection. However, non-white [[race]] is associated with worse [[prognosis]]. The 30-days [[mortality rate]] of aortic dissection type A and B is approximately 47% and 13%, respectively.
'''Associate Editor-In-Chief:''' {{CZ}}
 
==Epidemiology and Demographics==
==Epidemiology and Demographics==
 
===Incidence===
* Approximately 2000 cases in the US per year
*The [[incidence]] of aortic dissection is approximately 6 per 100,000 individuals worldwide.<ref name="HowardBanerjee2013">{{cite journal|last1=Howard|first1=Dominic P.J.|last2=Banerjee|first2=Amitava|last3=Fairhead|first3=Jack F.|last4=Perkins|first4=Jeremy|last5=Silver|first5=Louise E.|last6=Rothwell|first6=Peter M.|title=Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control|journal=Circulation|volume=127|issue=20|year=2013|pages=2031–2037|issn=0009-7322|doi=10.1161/CIRCULATIONAHA.112.000483}}</ref>
* Accounts for 3-4% of [[sudden deaths]]
===Age===
* 2:1 male:female predominance in all types of dissection.
*The [[incidence]] of aortic dissection increases with age, with a mean age of 63 years.<ref name="OlssonThelin2006">{{cite journal|last1=Olsson|first1=Christian|last2=Thelin|first2=Stefan|last3=Ståhle|first3=Elisabeth|last4=Ekbom|first4=Anders|last5=Granath|first5=Fredrik|title=Thoracic Aortic Aneurysm and Dissection|journal=Circulation|volume=114|issue=24|year=2006|pages=2611–2618|issn=0009-7322|doi=10.1161/CIRCULATIONAHA.106.630400}}</ref><ref>{{cite journal|title=Correspondence|journal=The Annals of Thoracic Surgery|volume=67|issue=2|year=1999|pages=593|issn=00034975|doi=10.1016/S0003-4975(99)00037-5}}</ref>
* Peak incidence in the sixth and seventh decades.
===Race===
**Patients with type I dissection present approximately 6 years younger than those with type II or type II dissection.
*There is no [[racial]] predilection to aortic dissection. However, non-white race is associated with worse [[prognosis]].<ref name="HarrisKlyushnenkova2016">{{cite journal|last1=Harris|first1=Donald|last2=Klyushnenkova|first2=Elena|last3=Kalsi|first3=Richa|last4=Garrido|first4=Danon|last5=Bhardwaj|first5=Abhishek|last6=Rabin|first6=Joseph|last7=Toursavadkohi|first7=Shahab|last8=Diaz|first8=Jose|last9=Crawford|first9=Robert|title=Non-White Race Is an Independent Risk Factor for Hospitalization for Aortic Dissection|journal=Ethnicity & Disease|volume=26|issue=3|year=2016|pages=363|issn=1945-0826|doi=10.18865/ed.26.3.363}}</ref>
* 67% present with acute symptoms (<2 weeks), and 33% with chronic symptoms (>= 2 weeks).
===Gender===
**Chronic dissection is almost twice as common in patients with type III (45%) when compared with type I (24%) and type II (27%).
*Men are more commonly affected by aortic dissection than women. However, the [[prognosis]] tends to be worse in women due to unusual presentations.<ref name="OlssonThelin2006">{{cite journal|last1=Olsson|first1=Christian|last2=Thelin|first2=Stefan|last3=Ståhle|first3=Elisabeth|last4=Ekbom|first4=Anders|last5=Granath|first5=Fredrik|title=Thoracic Aortic Aneurysm and Dissection|journal=Circulation|volume=114|issue=24|year=2006|pages=2611–2618|issn=0009-7322|doi=10.1161/CIRCULATIONAHA.106.630400}}</ref>
 
===Mortality rate===
*The 30-days [[mortality rate]] of aortic dissection type A and B is approximately 47% and 13% affected individuals, respectively.<ref name="HowardBanerjee2013">{{cite journal|last1=Howard|first1=Dominic P.J.|last2=Banerjee|first2=Amitava|last3=Fairhead|first3=Jack F.|last4=Perkins|first4=Jeremy|last5=Silver|first5=Louise E.|last6=Rothwell|first6=Peter M.|title=Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control|journal=Circulation|volume=127|issue=20|year=2013|pages=2031–2037|issn=0009-7322|doi=10.1161/CIRCULATIONAHA.112.000483}}</ref>
== References ==
== References ==
{{Reflist|2}}
{{Reflist|2}}


== Acknowledgements ==
The content on this page was first contributed by: David Feller-Kopman, MD and [[C. Michael Gibson]] M.S., M.D.
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Latest revision as of 17:29, 10 December 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Sahar Memar Montazerin, M.D.[2] Cafer Zorkun, M.D., Ph.D. [3]

Overview

The incidence of aortic dissection is approximately 6 per 100,000 individuals worldwide.The incidence of aortic dissection increases with age, with a mean age of 63 years. Men are more commonly affected by aortic dissection than women. However, the prognosis tends to be worse in women due to unusual presentations. There is no racial predilection to aortic dissection. However, non-white race is associated with worse prognosis. The 30-days mortality rate of aortic dissection type A and B is approximately 47% and 13%, respectively.

Epidemiology and Demographics

Incidence

  • The incidence of aortic dissection is approximately 6 per 100,000 individuals worldwide.[1]

Age

  • The incidence of aortic dissection increases with age, with a mean age of 63 years.[2][3]

Race

  • There is no racial predilection to aortic dissection. However, non-white race is associated with worse prognosis.[4]

Gender

  • Men are more commonly affected by aortic dissection than women. However, the prognosis tends to be worse in women due to unusual presentations.[2]

Mortality rate

  • The 30-days mortality rate of aortic dissection type A and B is approximately 47% and 13% affected individuals, respectively.[1]

References

  1. 1.0 1.1 Howard, Dominic P.J.; Banerjee, Amitava; Fairhead, Jack F.; Perkins, Jeremy; Silver, Louise E.; Rothwell, Peter M. (2013). "Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control". Circulation. 127 (20): 2031–2037. doi:10.1161/CIRCULATIONAHA.112.000483. ISSN 0009-7322.
  2. 2.0 2.1 Olsson, Christian; Thelin, Stefan; Ståhle, Elisabeth; Ekbom, Anders; Granath, Fredrik (2006). "Thoracic Aortic Aneurysm and Dissection". Circulation. 114 (24): 2611–2618. doi:10.1161/CIRCULATIONAHA.106.630400. ISSN 0009-7322.
  3. "Correspondence". The Annals of Thoracic Surgery. 67 (2): 593. 1999. doi:10.1016/S0003-4975(99)00037-5. ISSN 0003-4975.
  4. Harris, Donald; Klyushnenkova, Elena; Kalsi, Richa; Garrido, Danon; Bhardwaj, Abhishek; Rabin, Joseph; Toursavadkohi, Shahab; Diaz, Jose; Crawford, Robert (2016). "Non-White Race Is an Independent Risk Factor for Hospitalization for Aortic Dissection". Ethnicity & Disease. 26 (3): 363. doi:10.18865/ed.26.3.363. ISSN 1945-0826.

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