Adenocarcinoma of the lung history and symptoms: Difference between revisions

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==History and Symptoms==
==History and Symptoms==
*A positive history of smoking, family history of [[lung cancer]], radiation therapy to the chest, expsure to radon gas and asbestos is suggestive of adenocarcinoma of the lung.
*A positive history of smoking, family history of [[lung cancer]], [[radiation therapy]] to the chest, expsure to [[radon]] gas and [[asbestos]] is suggestive of adenocarcinoma of the [[lung]].
* The most common symptoms of adenocarcinoma of the lung include [[dyspnea]], [[hemoptysis]], chronic [[coughing]], [[Wheeze|wheezing]], [[chest pain]], [[abdominal pain]], [[cachexia]], [[fatigue]] and loss of [[appetite]].<ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on December 20, 2015</ref>  
* The most common symptoms of adenocarcinoma of the lung include [[dyspnea]], [[hemoptysis]], chronic [[coughing]], [[Wheeze|wheezing]], [[chest pain]], [[abdominal pain]], [[cachexia]], [[fatigue]] and loss of [[appetite]].<ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on December 20, 2015</ref>  
===History===
===History===
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* Exposure to high levels of air pollution  
* Exposure to high levels of air pollution  
* [[Radiation therapy]] to the chest  
* [[Radiation therapy]] to the chest  
* Expsure to radon gas  
* Expsure to [[radon]] gas  
* Exposure to [[asbestos]]  
* Exposure to [[asbestos]]  
* Exposure to high levels of [[arsenic]] in drinking water  
* Exposure to high levels of [[arsenic]] in drinking water  
* Occupational exposure to chemical carcinogens  
* Occupational exposure to [[Carcinogens|chemical carcinogens]]
* Previous lung disease  
* Previous [[Respiratory disease|lung disease]]
* Indoor burning of coal  
* Indoor burning of coal  
* [[SLE]]
* [[SLE]]
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* [[Dysphagia]]
* [[Dysphagia]]
* [[Superior vena cava syndrome]]
* [[Superior vena cava syndrome]]
* [[Neurological changes]]:
* [[Neurology|Neurological]] changes:
:* [[Weakness]]
:* [[Weakness]]
:* Numbness in extremities
:* Numbness in extremities
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:* [[Seizure]]
:* [[Seizure]]
* [[Lymphadenopathy]]
* [[Lymphadenopathy]]
* Symptoms due to paraneoplastic syndromes:<ref name="canadian" />  
* Symptoms due to [[Paraneoplastic syndrome|paraneoplastic syndromes]]:<ref name="canadian" />  
** Cancer cells release substances that affect the functioning of various organs, giving rise to a group of symptoms called paraneoplastic syndromes.  
** [[Cancer|Cancer cells]] release substances that affect the functioning of various [[Organ (anatomy)|organs]], giving rise to a group of symptoms called [[Paraneoplastic syndrome|paraneoplastic syndromes]].  
** [[Small cell lung cancer]] is more frequently associated with paraneoplastic syndromes, as compared to [[non–small cell lung cancer]].  
** [[Small cell lung cancer]] is more frequently associated with [[Paraneoplastic syndrome|paraneoplastic syndromes]], as compared to [[non–small cell lung cancer]].  
** Paraneoplastic syndromes presenting with adenocarcinoma of the lung include:<ref name="pmid25114839">{{cite journal |vauthors=Kanaji N, Watanabe N, Kita N, Bandoh S, Tadokoro A, Ishii T, Dobashi H, Matsunaga T |title=Paraneoplastic syndromes associated with lung cancer |journal=World J Clin Oncol |volume=5 |issue=3 |pages=197–223 |date=August 2014 |pmid=25114839 |pmc=4127595 |doi=10.5306/wjco.v5.i3.197 |url=}}</ref><ref name="pmid20810794">{{cite journal |vauthors=Pelosof LC, Gerber DE |title=Paraneoplastic syndromes: an approach to diagnosis and treatment |journal=Mayo Clin. Proc. |volume=85 |issue=9 |pages=838–54 |date=September 2010 |pmid=20810794 |pmc=2931619 |doi=10.4065/mcp.2010.0099 |url=}}</ref>
** [[Paraneoplastic syndrome|Paraneoplastic syndromes]] presenting with adenocarcinoma of the lung include:<ref name="pmid25114839">{{cite journal |vauthors=Kanaji N, Watanabe N, Kita N, Bandoh S, Tadokoro A, Ishii T, Dobashi H, Matsunaga T |title=Paraneoplastic syndromes associated with lung cancer |journal=World J Clin Oncol |volume=5 |issue=3 |pages=197–223 |date=August 2014 |pmid=25114839 |pmc=4127595 |doi=10.5306/wjco.v5.i3.197 |url=}}</ref><ref name="pmid20810794">{{cite journal |vauthors=Pelosof LC, Gerber DE |title=Paraneoplastic syndromes: an approach to diagnosis and treatment |journal=Mayo Clin. Proc. |volume=85 |issue=9 |pages=838–54 |date=September 2010 |pmid=20810794 |pmc=2931619 |doi=10.4065/mcp.2010.0099 |url=}}</ref>
*** [[Hypercalcemia]] (more commonly seen in [[squamous cell lung cancer]])  
*** [[Hypercalcemia]] (more commonly seen in [[squamous cell lung cancer]])  
*** [[Weakness]]  
*** [[Weakness]]  
*** Lack of coordination  
*** [[Ataxia|Lack of coordination]]
*** Changes in mental function  
*** Changes in [[mental function]]
*** High blood pressure  
*** High [[blood pressure]]
*** [[Nausea]]  
*** [[Nausea]]  
*** [[Vomiting]]  
*** [[Vomiting]]  
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**** Increased and sometimes painful growth of some bones, especially in the fingertips  
**** Increased and sometimes painful growth of some bones, especially in the fingertips  
**** Finger [[clubbing]]  
**** Finger [[clubbing]]  
**** Pain and swelling of bones and joints
**** Pain and swelling of bones and [[Joint|joints]]


==References==
==References==

Latest revision as of 14:37, 6 March 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Sudarshana Datta, MD [3]

Overview

The common symptoms of adenocarcinoma of the lung include dyspnea, hemoptysis, chronic coughing, chest pain, cachexia, dysphonia, and symptoms arising from paraneoplastic syndromes such as weakness, lack of coordination, changes in mental function, high blood pressure, nausea and vomiting.

History and Symptoms

History

Patients with adenocarcinoma of the lung may have a positive history of:

Common Symptoms

Common symptoms of adenocarcinoma of the lung include:[2]

Less Common Symptoms

Less common and late symptoms of adenocarcinoma of the lung include:[1]

References

  1. 1.0 1.1 1.2 Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on December 20, 2015
  2. Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter |coauthors= ignored (help)
  3. Kanaji N, Watanabe N, Kita N, Bandoh S, Tadokoro A, Ishii T, Dobashi H, Matsunaga T (August 2014). "Paraneoplastic syndromes associated with lung cancer". World J Clin Oncol. 5 (3): 197–223. doi:10.5306/wjco.v5.i3.197. PMC 4127595. PMID 25114839.
  4. Pelosof LC, Gerber DE (September 2010). "Paraneoplastic syndromes: an approach to diagnosis and treatment". Mayo Clin. Proc. 85 (9): 838–54. doi:10.4065/mcp.2010.0099. PMC 2931619. PMID 20810794.


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