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'''8-Hydroxyquinoline''', or '''oxyquinoline''', is an [[organic compound]] with the formula C<sub>9</sub>H<sub>7</sub>NO, a derivative of [[quinoline]].  It is usually extracted from [[coal tar]].<ref>[http://www.chemistry.org/portal/a/c/s/1/acsdisplay.html?id=c373e9114f4db7be8f6a17245d830100 American Chemical Society]</ref> This white compound is widely used as a chelating agent, where it binds to metals as a bidentate ligand. It is widely used commercially, although under a variety of names.<ref name="multiple">[http://ptcl.chem.ox.ac.uk/MSDS/HY/8-hydroxyquinoline.html Oxford University 8-hydroxyquinoline Safety Data]</ref><ref>[http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35563 Pesticide Database]</ref>  
'''8-Hydroxyquinoline''', or '''oxyquinoline''', is an [[organic compound]] with the formula C<sub>9</sub>H<sub>7</sub>NO, a derivative of [[quinoline]].  It is usually extracted from [[coal tar]].<ref>[http://www.chemistry.org/portal/a/c/s/1/acsdisplay.html?id=c373e9114f4db7be8f6a17245d830100 American Chemical Society]</ref> This white compound is widely used as a chelating agent, where it binds to metals as a bidentate ligand. It is widely used commercially, although under a variety of names.<ref name="multiple">[http://ptcl.chem.ox.ac.uk/MSDS/HY/8-hydroxyquinoline.html Oxford University 8-hydroxyquinoline Safety Data]</ref><ref>[http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35563 Pesticide Database]</ref>  

Revision as of 19:07, 8 August 2012

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8-Hydroxyquinoline, or oxyquinoline, is an organic compound with the formula C9H7NO, a derivative of quinoline. It is usually extracted from coal tar.[1] This white compound is widely used as a chelating agent, where it binds to metals as a bidentate ligand. It is widely used commercially, although under a variety of names.[2][3]

It is used as a metal chelator, antiseptic, disinfectant and pesticide.[4][5] Its solution in alcohol are used as liquid bandages. It once was of interest as an anti-cancer drug.[6]

The roots of the invasive plant Centaurea diffusa release the 8-hydroxyquinoline, which has a negative effect on plants that have not co-evolved with it.

Safety

See MSDS.[2]

References

  1. American Chemical Society
  2. 2.0 2.1 Oxford University 8-hydroxyquinoline Safety Data
  3. Pesticide Database
  4. Phillips, J. P. “The Reactions Of 8-Quinolinol” Chemical Reviews 1956, volume 56, pp 271 - 297; DOI: 10.1021/cr50008a003
  5. Medical Dictionary Online
  6. Shen AY, Wu SN, Chiu CT (1999). "Synthesis and cytotoxicity evaluation of some 8-hydroxyquinoline derivatives". J. Pharm. Pharmacol. 51 (5): 543–8. PMID 10411213.


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