Non-bacterial thrombotic endocarditis epidemiology and demographics

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non-bacterial thrombotic endocarditis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aisha Adigun, B.Sc., M.D.[2]

Overview

Epidemiology and Demographics

Incidence

  • Non-bacterial thrombotic endocarditis is a rare autopsy finding[1].
  • It is a rare disease that tends to affect patients with advanced malignancies[2][3] and patients with autoimmune disorders[4].
  • Although the exact incidence of NBTE is unknown, it is thought to be approximately 900-600 per 100,000 individuals worldwide[5][6].

Prevalence

  • The prevalence of NBTE is approximately 9,300 per 100,000 individuals worldwide[7].

Age

  • Patients of all age groups may develop NBTE[8].
  • NBTE commonly affects individuals between the ages of 40-80years of age[7][9].

Race

  • There is no racial predilection to NBTE[8].

Gender

  • NBTE affects men and women equally[7][8].



References

  1. Llenas-García J, Guerra-Vales JM, Montes-Moreno S, López-Ríos F, Castelbón-Fernández FJ, Chimeno-García J (May 2007). "[Nonbacterial thrombotic endocarditis: clinicopathologic study of a necropsy series]". Rev Esp Cardiol (in Spanish; Castilian). 60 (5): 493–500. PMID 17535760.
  2. Edoute Y, Haim N, Rinkevich D, Brenner B, Reisner SA (March 1997). "Cardiac valvular vegetations in cancer patients: a prospective echocardiographic study of 200 patients". Am. J. Med. 102 (3): 252–8. doi:10.1016/S0002-9343(96)00457-3. PMID 9217593.
  3. Kalangos A, Pretre R, Girardet C, Ricou E, Faidutti B (February 1997). "An atypical aortic valve non-bacterial thrombotic endocarditis in the course of multiple myeloma". Eur. Heart J. 18 (2): 351–2. doi:10.1093/oxfordjournals.eurheartj.a015243. PMID 9043857.
  4. Hojnik M, George J, Ziporen L, Shoenfeld Y (April 1996). "Heart valve involvement (Libman-Sacks endocarditis) in the antiphospholipid syndrome". Circulation. 93 (8): 1579–87. doi:10.1161/01.cir.93.8.1579. PMID 8608627.
  5. Deppisch LM, Fayemi AO (December 1976). "Non-bacterial thrombotic endocarditis: clinicopathologic correlations". Am. Heart J. 92 (6): 723–9. doi:10.1016/s0002-8703(76)80008-7. PMID 998478.
  6. González Quintela A, Candela MJ, Vidal C, Román J, Aramburo P (1991). "Non-bacterial thrombotic endocarditis in cancer patients". Acta Cardiol. 46 (1): 1–9. PMID 1851590.
  7. 7.0 7.1 7.2 Kuramoto K, Matsushita S, Yamanouchi H (September 1984). "Nonbacterial thrombotic endocarditis as a cause of cerebral and myocardial infarction". Jpn. Circ. J. 48 (9): 1000–6. doi:10.1253/jcj.48.1000. PMID 6481938.
  8. 8.0 8.1 8.2 Lopez JA, Ross RS, Fishbein MC, Siegel RJ (March 1987). "Nonbacterial thrombotic endocarditis: a review". Am. Heart J. 113 (3): 773–84. doi:10.1016/0002-8703(87)90719-8. PMID 3548296.
  9. ANGRIST A, MARQUISS J (1954). "The changing morphologic picture of endocarditis since the advent of chemotherapy and antibiotic agents". Am. J. Pathol. 30 (1): 39–63. PMC 1942455. PMID 13124459.

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