Barrett's esophagus historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Historical Perspective

The condition is named after Dr. Norman Barrett (1903–1979), Australian-born British surgeon at St Thomas' Hospital, who described the condition in 1957.[1]

Norman Barrett, in 1950, defined the esophagus as, ‘that part of the foregut, distal to the cricopharyngeal sphincter, which is lined by squamous epithelium’. It is ironic, then, that columnar metaplasia of the esophagus is referred to as Barrett’s esophagus (BE). Tileston, however, was the first to describe columnar metaplasia of the esophagus in 1906, as ‘peptic ulcer of the esophagus’.

Historical Perspective

Discovery

  • [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event]
  • The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
  • In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
  • In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

Outbreaks

  • There have been several outbreaks of [disease name], which are summarized below:

Landmark Events in the Development of Treatment Strategies

  • In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

Impact on Cultural History

Famous Cases

References

  1. Barrett N (1957). "The lower esophagus lined by columnar epithelium". Surgery. 41 (6): 881–94. PMID 13442856.

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