Esthesioneuroblastoma pathophysiology

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Esthesioneuroblastoma Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Pathophysiology

Olfactory neuroblastomas are of neural crest cell origin 1. They are mulilobulated pink-grey tumors. Histology demonstrates variable differentiation, from well formed neural tissue to undifferentiated neuroblasts with pseudorosette formation 2. It has been suggested that olfactory neuroblastoma is actually part of the Ewing sarcoma group of tumours, rather than being related to neuroblastoma.

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References

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