Kaposi's sarcoma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

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Overview

Kaposi's sarcoma must be differentiated from other diseases that cause similar cutaneous, pulmonary, and gastrointestinal involvement, such as bacillary angiomatosis, AIDS-related lymphoma, and seborrheic keratosis.[1][2][3]

Differentiating Kaposi's Sarcoma from other Diseases

  • Kaposi's sarcoma cutaneous lesions must be differentiated from:
  • Kaposi's sarcoma pulmonary lesions must be differentiated from:
  • Kaposi's sarcoma gastrointestinal lesions must be differentiated from:
Etiology Clinical manifestations Lab findings Microscopic findings Diagnosis
Diseases Congenital Acquied Lymphadenopathy Fever CBC LFT ESR/CRP Histopathology Gold standard Additional findings
Bacillary angiomatosis
  • HIV
  • Chronic lymphocytic leukemia
  • Cytotoxic chemotherapy
  • Organ transplantation
Arteriovenous malformation
Acroangiodermatitis
Angiosarcoma
Masson's hemangioma
Seborrheic keratosis
Systemic lupus erythematosus (SLE)
Pigmented purpuric dermatosis
Pyogenic granuloma
Benign lymphangioendothelioma
Cavernous hemangioma
Sarcomatoid carcinoma
Spindle cell hemangioendothelioma

References

  1. 1.0 1.1 Kaposi's Sarcoma. Radiopaedia (2015) http://radiopaedia.org/articles/kaposi-sarcoma Accessed on January, 19 2016
  2. 2.0 2.1 Libre Pathology. Kaposi's sarcoma (2015) http://librepathology.org/wiki/index.php/File:Kaposi_sarcoma_low_intermed_mag.jpg Accessed on January, 19 2016
  3. 3.0 3.1 Kaposi's Sarcoma. PathologyOutlines (2015) http://www.pathologyoutlines.com/topic/skintumornonmelanocytickaposisarcoma.html Accessed on January, 19 2015

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