Boil pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Boil(furuncle) is a localized, deep, suppurative, necrotizing form of folliculitis which involves dermis and subcutaneous tissue. Staphylococcus aureus is the most common causative agent. Following an abrasion or cut the pathogen uses the entry site to invade and colonize the hair follicle leading to the formation of tender, red, perifollicular nodule. It later becomes painful and fluctuant terminating in the discharge of pus and necrotic plug which may leave a scar.[1]

Pathophysiology

Pathogenesis

  • Group of furuncles coalesce to form carbuncle.

Associated Conditions

Gross Pathology

On gross pathology, the following are characteristic findings of boil(furuncle):

  • It begins as a firm, tender, red, dome shaped nodule
  • It later becomes fluctuant (Pus filled) and painful
  • They vary in size

Microscopic histopathological analysis

On microscopic histopathological analysis, the following are characteristic findings of boil(furuncle):

  • Superficial(primarily involving the infandibulum)
  • Deep

Images

The following are the images associated with boil(furuncle).

References

  1. 1.0 1.1 1.2 Ibler KS, Kromann CB (2014). "Recurrent furunculosis - challenges and management: a review". Clin Cosmet Investig Dermatol. 7: 59–64. doi:10.2147/CCID.S35302. PMC 3934592. PMID 24591845.
  2. wikipedia. Furuncle (2016) https://en.wikipedia.org/wiki/Boil#/media/File:Furoncle.jpg Accessed on August 8,2016
  3. Principles of Pediatric Dermatology. Bacterial skin infections http://www.drmhijazy.com/english/chapters/chapter06.htm Accessed on August 10,2016


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