Glucose-6-phosphate dehydrogenase deficiency history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The majority of patients with G6PD deficiencyare asymptomatic. Common symptoms of G6PD include nausea, back pain, | The majority of patients with G6PD deficiencyare [[asymptomatic]]. Common symptoms of G6PD include [[nausea]], [[back pain]], [[headache]], [[chills]]. Less common symptoms include [[acute renal failure]] and [[shortness of breath]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
*The majority of patients with G6PD deficiency are asymptomatic. | *The majority of patients with G6PD deficiency are [[asymptomatic]]. | ||
===History=== | ===History=== | ||
Patients with G6PD deficiency may have a positive history of: | Patients with G6PD deficiency may have a positive history of: | ||
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===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of G6PD include: | Common symptoms of G6PD include: | ||
*Acute intravascular hemolysis | *Acute [[intravascular]] [[hemolysis]] 5 to 24 hours after ingestion [[Fava bean|fava]] beans ( [[favism]]):<ref name="pmid29298156">{{cite journal |vauthors=Luzzatto L, Arese P |title=Favism and Glucose-6-Phosphate Dehydrogenase Deficiency |journal=N. Engl. J. Med. |volume=378 |issue=1 |pages=60–71 |date=January 2018 |pmid=29298156 |doi= |url=}}</ref> | ||
**Most in male children ( ages1-5 years) | **Most in male children ( ages1-5 years) | ||
** | **[[Headache]] | ||
**Nausea | **[[Nausea]] | ||
**Back pain | **[[Back pain]] | ||
** | **[[Chills]] | ||
**Fever | **[[Fever]] | ||
**Jaundice | **[[Jaundice]] | ||
** | ** | ||
*Feeling tired | *Feeling tired | ||
| Line 28: | Line 28: | ||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of G6PD deficiency include<ref name="pmid23841200">{{cite journal |vauthors=Burka ER, Weaver Z, Marks PA |title=Clinical spectrum of hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency |journal=Ann. Intern. Med. |volume=64 |issue=4 |pages=817–25 |date=April 1966 |pmid=23841200 |doi= |url=}}</ref> | Less common symptoms of G6PD deficiency include<ref name="pmid23841200">{{cite journal |vauthors=Burka ER, Weaver Z, Marks PA |title=Clinical spectrum of hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency |journal=Ann. Intern. Med. |volume=64 |issue=4 |pages=817–25 |date=April 1966 |pmid=23841200 |doi= |url=}}</ref> | ||
*Acute renal failure<ref name="pmid5695625">{{cite journal |vauthors=Whelton A, Donadio JV, Elisberg BL |title=Acute renal failure complicating rickettsial infections in glucose-6-phosphate dehydrogenase-deficient individuals |journal=Ann. Intern. Med. |volume=69 |issue=2 |pages=323–8 |date=August 1968 |pmid=5695625 |doi= |url=}}</ref> | *[[Acute renal failure]]<ref name="pmid5695625">{{cite journal |vauthors=Whelton A, Donadio JV, Elisberg BL |title=Acute renal failure complicating rickettsial infections in glucose-6-phosphate dehydrogenase-deficient individuals |journal=Ann. Intern. Med. |volume=69 |issue=2 |pages=323–8 |date=August 1968 |pmid=5695625 |doi= |url=}}</ref> | ||
*Shortness of breath | *[[Shortness of breath]] | ||
* | * | ||
==References== | ==References== | ||
Revision as of 20:53, 27 August 2018
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- Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
The majority of patients with G6PD deficiencyare asymptomatic. Common symptoms of G6PD include nausea, back pain, headache, chills. Less common symptoms include acute renal failure and shortness of breath.
History and Symptoms
- The majority of patients with G6PD deficiency are asymptomatic.
History
Patients with G6PD deficiency may have a positive history of:
- Similar problems in family
Common Symptoms
Common symptoms of G6PD include:
- Acute intravascular hemolysis 5 to 24 hours after ingestion fava beans ( favism):[1]
- Feeling tired
Less Common Symptoms
Less common symptoms of G6PD deficiency include[2]
References
- ↑ Luzzatto L, Arese P (January 2018). "Favism and Glucose-6-Phosphate Dehydrogenase Deficiency". N. Engl. J. Med. 378 (1): 60–71. PMID 29298156.
- ↑ Burka ER, Weaver Z, Marks PA (April 1966). "Clinical spectrum of hemolytic anemia associated with glucose-6-phosphate dehydrogenase deficiency". Ann. Intern. Med. 64 (4): 817–25. PMID 23841200.
- ↑ Whelton A, Donadio JV, Elisberg BL (August 1968). "Acute renal failure complicating rickettsial infections in glucose-6-phosphate dehydrogenase-deficient individuals". Ann. Intern. Med. 69 (2): 323–8. PMID 5695625.