Glucose-6-phosphate dehydrogenase deficiency physical examination

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Glucose-6-phosphate dehydrogenase deficiency Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [3]

Overview

Patients with G6PD deficiency usually appear normal. Physical examination of patients with G6PD deficiency is usually remarkable for jaundice in hemolysis and abdominal tenderness in the right upper abdominal quadrant because of hyperbilirubinemia.

Physical Examination

Physical examination of patients with G6PD deficiency is usually normal.

Appearance of the Patient

  • Patients with G6PD deficiency usually appear normal.

Vital Signs

Skin

  • Jaundice in hemolysis [1]
  • Pallor

HEENT

  • HEENT examination of patients with G6PD deficiency is usually normal

Neck

  • Neck examination of patients with G6PD deficiency is usually normal

Lungs

  • Pulmonary examination of patients with G6PD deficiency is usually normal

Heart

  • Cardiovascular examination of patients with G6PD deficiency is usually normal

Abdomen

Genitourinary

  • Dark urine
  • Genitourinary examination of patients with G6PD deficiency is usually normal

Neuromuscular

  • Neuromuscular examination of patients with G6PD deficiency is usually normal

Extremities

  • Extremities examination of patients with G6PD deficiency is usually normal

References

  1. Luzzatto L, Arese P (January 2018). "Favism and Glucose-6-Phosphate Dehydrogenase Deficiency". N. Engl. J. Med. 378 (1): 60–71. PMID 29298156.
  2. Arese P, Gallo V, Pantaleo A, Turrini F (October 2012). "Life and Death of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficient Erythrocytes - Role of Redox Stress and Band 3 Modifications". Transfus Med Hemother. 39 (5): 328–34. doi:10.1159/000343123. PMC 3678266. PMID 23801924.

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