Gastroparesis causes: Difference between revisions
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==Overview== | ==Overview== | ||
The [[etiology]] of gastroparesis can be broadly classified into idiopathic, | |||
==Causes== | ==Causes== | ||
===Life | ===Life threatening causes=== | ||
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. | Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. | ||
* [[Brainstem stroke]] | * [[Brainstem stroke]] | ||
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<font color="white">{{Smallcaps|{{PAGENAME}} developed by WikiDoc.org}}</font> | <font color="white">{{Smallcaps|{{PAGENAME}} developed by WikiDoc.org}}</font> | ||
===Common | ===Common causes=== | ||
* | *Gastroparesis most commonly has an idiopathic etiology<ref name="pmid19410575">{{cite journal| author=Hyett B, Martinez FJ, Gill BM, Mehra S, Lembo A, Kelly CP et al.| title=Delayed radionucleotide gastric emptying studies predict morbidity in diabetics with symptoms of gastroparesis. | journal=Gastroenterology | year= 2009 | volume= 137 | issue= 2 | pages= 445-52 | pmid=19410575 | doi=10.1053/j.gastro.2009.04.055 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19410575 }}</ref>. Most common symptoms of idiopathic gastroparesis were consistent with viral etiology and after cholecystectomy.<ref name="pmid25667019">{{cite journal| author=Bharucha AE| title=Epidemiology and natural history of gastroparesis. | journal=Gastroenterol Clin North Am | year= 2015 | volume= 44 | issue= 1 | pages= 9-19 | pmid=25667019 | doi=10.1016/j.gtc.2014.11.002 | pmc=4323583 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25667019 }}</ref> cholecystectomy was also common among diabetic gastroparesis patient subgroup. | ||
*Diabetes mellitus (Type II is more common cause than type I DM)<ref name="pmid19410575" /> - second commonest cause | *Diabetes mellitus (Type II is more common cause than type I DM)<ref name="pmid19410575" /> - second commonest cause | ||
*Post- surgical: Distal gastrectomy for cancer stomach, pancreatoduodenectomy, cholecystectomy, fundoplication etc.<ref name="pmid28320386">{{cite journal| author=Glowka TR, Webler M, Matthaei H, Schäfer N, Schmitz V, Kalff JC et al.| title=Delayed gastric emptying following pancreatoduodenectomy with alimentary reconstruction according to Roux-en-Y or Billroth-II. | journal=BMC Surg | year= 2017 | volume= 17 | issue= 1 | pages= 24 | pmid=28320386 | doi=10.1186/s12893-017-0226-x | pmc=5359898 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28320386 }}</ref> | *Post- surgical: Distal gastrectomy for cancer stomach, pancreatoduodenectomy, cholecystectomy, fundoplication etc.<ref name="pmid28320386">{{cite journal| author=Glowka TR, Webler M, Matthaei H, Schäfer N, Schmitz V, Kalff JC et al.| title=Delayed gastric emptying following pancreatoduodenectomy with alimentary reconstruction according to Roux-en-Y or Billroth-II. | journal=BMC Surg | year= 2017 | volume= 17 | issue= 1 | pages= 24 | pmid=28320386 | doi=10.1186/s12893-017-0226-x | pmc=5359898 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28320386 }}</ref> |
Revision as of 21:15, 6 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2] Farman Khan, MD, MRCP [3]
Overview
The etiology of gastroparesis can be broadly classified into idiopathic,
Causes
Life threatening causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Gastroparesis causes developed by WikiDoc.org
Common causes
- Gastroparesis most commonly has an idiopathic etiology[1]. Most common symptoms of idiopathic gastroparesis were consistent with viral etiology and after cholecystectomy.[2] cholecystectomy was also common among diabetic gastroparesis patient subgroup.
- Diabetes mellitus (Type II is more common cause than type I DM)[1] - second commonest cause
- Post- surgical: Distal gastrectomy for cancer stomach, pancreatoduodenectomy, cholecystectomy, fundoplication etc.[3]
- Narcotics
- Phenothiazines
- Pregnancy
- Scleroderma
- Systemic sclerosis
- Vagotomy
Gastroparesis causes developed by WikiDoc.org
Causes by Organ System
Cardiovascular | percutaneous catheter ablation for atrial fibrillation; prevalence of gastroparesis after radio-frequency ablation is 10% and cryoablation procedures is 6%, respectively.[4] |
Chemical/Poisoning | No underlying causes |
Dental | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect | Tricyclic antidepressants, Phenothiazines, Octreotide, Narcotics, Muscarinic cholinergic receptor antagonists,
Glucagon-like peptide (GLP)-1 agonists, Amylin analogues, Dopamine agonists, Cholangiocarcinoma, Calcium channel blockers, Anticholinergics, Alpha-2-adrenergic agonists |
Ear Nose Throat | No underlying causes |
Endocrine | Hypothyroidism, Hypoparathyroidism, Diabetes mellitus type 2, Diabetes mellitus type 1 |
Environmental | No underlying causes |
Gastroenterologic | Ulcers in first portion of duodenum, Pyloric stenosis, Pyloric channel ulcer, Pancreatic pseudocyst, Pancreatic cancer,
Gastroesophageal reflux disease, Gastric polyps, Gastric cancer, Duodenal cancer, Abdominal migraine |
Genetic | No underlying causes |
Hematologic | No underlying causes |
Iatrogenic | Surgery on the stomach or vagus nerve, Complication of stomach surgery for ulcer disease or weight loss,Vagotomy |
Infectious Disease | Rotavirus, Postviral syndromes, Norwalk virus, AIDS, Acute viral infection |
Musculoskeletal/Orthopedic | No underlying causes |
Neurologic | Primary dysautonomias, Parkinson's disease, Brainstem stroke or tumor, Autonomic neuropathy, Autoimmune gastrointestinal dysmotility |
Nutritional/Metabolic | No underlying causes |
Obstetric/Gynecologic | Pregnancy |
Oncologic | Ampullary cancer |
Ophthalmologic | No underlying causes |
Overdose/Toxicity | No underlying causes |
Psychiatric | Psychogenic, vomiting, Depression, Bulimia, Anxiety neurosis, Anorexia nervosa |
Pulmonary | Small cell lung cancer |
Renal/Electrolyte | Kidney failure, Hypomagnesemia, Hypokalemia |
Rheumatology/Immunology/Allergy | Systemic sclerosis, Sclerodema, Polymyositis, Lupus |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | Myotonic dystrophy, Idiopathic, Congenital obstruction, Bouveret Syndrome, Amyloidosis , Amyloid neuropathy |
Gastroparesis causes developed by WikiDoc.org
Causes in Alphabetical Order
Gastroparesis causes developed by WikiDoc.org
Transient gastroparesis may arise in acute illness of any kind,
- Certain cancer treatments or other drugs which affect digestive action,
- Anorexia
- Bulimia
- Other abnormal eating patterns.
- Medications(anticholinergics and narcotics)that slow contractions in the intestine
Chronic gastroparesis is frequently due to autonomic neuropathy.
- Type 1 diabetes or type 2 diabetes: The vagus nerve becomes damaged by years of high blood glucose, resulting in gastroparesis. Fibromyalgia
- Parkinson's disease
- Mitochondrial disorder.
- Abdominal surgery.[7]
- Amyloidosis
- Scleroderma
- Abdominal migraine
- Hypothyroidism
- Gastroesophageal reflux disease
Idiopathic gastroparesis (gastroparesis with no known cause) accounts for a third of all chronic cases; it is thought that many of these cases are due to an autoimmune response triggered by an acute viral infection
- Stomach flu
- Mononucleosis, and others have been anecdotally linked to the onset of the condition, but no systematic study has proven a link.
References
- ↑ 1.0 1.1 Hyett B, Martinez FJ, Gill BM, Mehra S, Lembo A, Kelly CP; et al. (2009). "Delayed radionucleotide gastric emptying studies predict morbidity in diabetics with symptoms of gastroparesis". Gastroenterology. 137 (2): 445–52. doi:10.1053/j.gastro.2009.04.055. PMID 19410575.
- ↑ Bharucha AE (2015). "Epidemiology and natural history of gastroparesis". Gastroenterol Clin North Am. 44 (1): 9–19. doi:10.1016/j.gtc.2014.11.002. PMC 4323583. PMID 25667019.
- ↑ Glowka TR, Webler M, Matthaei H, Schäfer N, Schmitz V, Kalff JC; et al. (2017). "Delayed gastric emptying following pancreatoduodenectomy with alimentary reconstruction according to Roux-en-Y or Billroth-II". BMC Surg. 17 (1): 24. doi:10.1186/s12893-017-0226-x. PMC 5359898. PMID 28320386.
- ↑ Aksu T, Golcuk S, Guler TE, Yalin K, Erden I (2015). "Gastroparesis as a Complication of Atrial Fibrillation Ablation". Am J Cardiol. 116 (1): 92–7. doi:10.1016/j.amjcard.2015.03.045. PMID 25933733.
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ Gastroparesis: Causes - MayoClinic.com