Necrotizing fasciitis laboratory findings: Difference between revisions
No edit summary |
No edit summary |
||
Line 27: | Line 27: | ||
*Urine analysis | *Urine analysis | ||
*Elevated Blood urea nitrogen (BUN) | *Elevated Blood urea nitrogen (BUN) | ||
===Hematology=== | |||
The following are complete blood count with differential findings: | |||
:*Rapidly falling heamoglobin | |||
:*Leucocytosis (>14,000/µL) | |||
:*Leucopenia (if associated with STSS) | |||
:*Lymphopenia | |||
:*Thrombocytopenia | |||
===Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system=== | ===Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system=== | ||
Line 115: | Line 123: | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Surgery]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] |
Revision as of 18:58, 9 September 2016
Necrotizing fasciitis Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Necrotizing fasciitis laboratory findings On the Web |
American Roentgen Ray Society Images of Necrotizing fasciitis laboratory findings |
Risk calculators and risk factors for Necrotizing fasciitis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Laboratory Findings
Laboratory tests consistent with diagnosis of necrotizing fasciitis include:
Microbiology
The following are the tests used to diagnose the causative organism:
- Gram stain and culture of tissues and aspirates
- Blood culture
- Culture of throat and vaginal swabs
- Fungal culture (immunocompromised or trauma patients)
- Enrichment cultures (patients with recent antibiotic use)
Boichemistry
The biochemistry findings consistent with diagnosis of necrotizing fasciitis include:
- Elevated C-reactive protein
- Elevated serum creatinine kinase
- Hypocalcemia (sign of severity in synergistic NF)
- Hypoalbuminemia
- Hyponatremia (<135mmol/L)
- Elevated serum lactate levels (high serum lactate combined with low sodium levels may be predictive of mortality)
- Arterial blood gas analysis
- Urine analysis
- Elevated Blood urea nitrogen (BUN)
Hematology
The following are complete blood count with differential findings:
- Rapidly falling heamoglobin
- Leucocytosis (>14,000/µL)
- Leucopenia (if associated with STSS)
- Lymphopenia
- Thrombocytopenia
Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system
- LRINEC is a diagnostic scoring system used to distinguish necrotizing fasciitis from other soft tissue infections.[1]
- It was first established by Wong et al in 2004.
- Risk assessment of necrotizing faciitis using LRINEC score:
- Low risk: ≤5
- Intermediate risk: 6-7
- High risk: ≥8
Variable | Score |
---|---|
C- reactive protein (mg/dL)
<150 |
0 |
Total white blood cell count (/mm3)
<15 |
0 |
Hemoglobin (g/dL)
<13.5 |
0 |
Sodium (mmol/L)
≥135 |
0 |
Creatinine (μmol/L)
<141 |
0 |
Glucose (mmol/L)
<10 |
0 |
References
- ↑ Wong CH, Khin LW, Heng KS, Tan KC, Low CO (2004). "The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections". Crit Care Med. 32 (7): 1535–41. PMID 15241098.