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Revision as of 17:34, 5 January 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
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Overview
Pertussis was recognizably described as early as 1578 by Guillaume de Baillou (1538-1616), but earlier reports date back at least to the 12th century.[1] B. pertussis was isolated in pure culture in 1906 by Jules Bordet and Octave Gengou, who also developed the first serology and vaccine. The complete B. pertussis genome of 4,086,186 base pairs was sequenced in 2002.
Historical Perspective
Discovery
- The earliest evidence of people displaying symptoms of Pertussis occurred during the Middle Ages, described as "the kink" or "the kindhoest" in Scotland to indicate a cough or fit.[2]
- The first offically recognized outbreak of Pertussis was in 1502 in the former Persian Empire, recorded by Persian Physician Bahaodowle Razi.[3]
- Pertussis was first officially recognized in Europe by French physician Guillaume de Baillou in 1578 during its outbreak in Paris.[2].
- The causative organism, Bordetella pertussis, was discovered and isolated in 1906 by Belgian biologists Jules Bordet and Octave Gengou.
Development of Treatment Strategies
- Jules Bordet and Octave Gengou developed the first vaccine and serological test for Pertussis following discovery of Bordetella pertussis.
- In 1942, American scientists Grace Eldering, Loney Gordon, and Pearl Kendrick combined the whole-cell pertussis vaccine with diphtheria and tetanus toxoids to generate the first DTP combination vaccine.
- In 1981 an acelluar vaccine was created in Japan and was added, in 1992, to the DTP Vaccine to create the DTaP vaccine, which had a much smaller rate of adverse side effects.[4]
References
- ↑ Versteegh FGA, Schellekens JFP, Fleer A, Roord JJ. (2005). "Pertussis: a concise historical review including diagnosis, incidence, clinical manifestations and the role of treatment and vaccination in management". Rev Med Microbiol. 16 (3): 79–89.
- ↑ 2.0 2.1 Cherry, James D. (November 1996). "Historical Review of Pertussis and the Classical Vaccine" (PDF). Journal of Infectious Diseases. Oxford. 174 (3): 259–263. Retrieved 5 January 2016.
- ↑ Yarmohammadi H, Bahmani Kazeruni MH, Soofi A, Zargaran A (2015). "The First Report of Epidemic Pertussis by Bahaodowle Razi From the 15th Century Anno Domini". Iran Red Crescent Med J. 17 (7): e13454. doi:10.5812/ircmj.13454. PMC 4580069. PMID 26413316.
- ↑ Pichichero ME, Rennels MB, Edwards KM, Blatter MM, Marshall GS, Bologa M; et al. (2005). "Combined tetanus, diphtheria, and 5-component pertussis vaccine for use in adolescents and adults". JAMA. 293 (24): 3003–11. doi:10.1001/jama.293.24.3003. PMID 15933223. Review in: Evid Based Med. 2006 Apr;11(2):51