Multiple endocrine neoplasia type 2 cost-effectiveness of therapy: Difference between revisions
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==Cost-Effectiveness of Therapy== | ==Cost-Effectiveness of Therapy== | ||
===Methods for cost effectiveness of the therapy=== | ===Methods for cost effectiveness of the therapy=== | ||
* Molecular screening of RET gene limiting to exon 10,11 and 16 is an effective way of reducing the cost of management of | * Molecular screening of RET gene limiting to exon 10,11 and 16 is an effective way of reducing the cost of management of thyroidectomy. | ||
* For diagnosis of multiple endocrine neoplasia type 2B, investigation of exon 16 is adequate and this further is a cost effective method.<ref name="pmid19443294">{{cite journal| author=Chang CF, Yang WS, Su YN, Wu IL, Chang TC| title=Mutational spectrum of multiple endocrine neoplasia type 2 and sporadic medullary thyroid carcinoma in taiwan. | journal=J Formos Med Assoc | year= 2009 | volume= 108 | issue= 5 | pages= 402-8 | pmid=19443294 | doi=10.1016/S0929-6646(09)60084-X | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19443294 }} </ref> | * For diagnosis of multiple endocrine neoplasia type 2B, investigation of exon 16 is adequate and this further is a cost effective method.<ref name="pmid19443294">{{cite journal| author=Chang CF, Yang WS, Su YN, Wu IL, Chang TC| title=Mutational spectrum of multiple endocrine neoplasia type 2 and sporadic medullary thyroid carcinoma in taiwan. | journal=J Formos Med Assoc | year= 2009 | volume= 108 | issue= 5 | pages= 402-8 | pmid=19443294 | doi=10.1016/S0929-6646(09)60084-X | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19443294 }} </ref> | ||
* Prophylactic thyroidectomy of patients screened positive for RET gene is a cost effective way of management of thyroidectomy.<ref name="pmid11981210">{{cite journal| author=Cohen MS, Phay JE, Albinson C, DeBenedetti MK, Skinner MA, Lairmore TC et al.| title=Gastrointestinal manifestations of multiple endocrine neoplasia type 2. | journal=Ann Surg | year= 2002 | volume= 235 | issue= 5 | pages= 648-54; discussion 654-5 | pmid=11981210 | doi= | pmc=PMC1422490 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11981210 }} </ref> | |||
==References== | ==References== | ||
Revision as of 23:56, 28 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Cost-Effectiveness of Therapy
Methods for cost effectiveness of the therapy
- Molecular screening of RET gene limiting to exon 10,11 and 16 is an effective way of reducing the cost of management of thyroidectomy.
- For diagnosis of multiple endocrine neoplasia type 2B, investigation of exon 16 is adequate and this further is a cost effective method.[1]
- Prophylactic thyroidectomy of patients screened positive for RET gene is a cost effective way of management of thyroidectomy.[2]
References
- ↑ Chang CF, Yang WS, Su YN, Wu IL, Chang TC (2009). "Mutational spectrum of multiple endocrine neoplasia type 2 and sporadic medullary thyroid carcinoma in taiwan". J Formos Med Assoc. 108 (5): 402–8. doi:10.1016/S0929-6646(09)60084-X. PMID 19443294.
- ↑ Cohen MS, Phay JE, Albinson C, DeBenedetti MK, Skinner MA, Lairmore TC; et al. (2002). "Gastrointestinal manifestations of multiple endocrine neoplasia type 2". Ann Surg. 235 (5): 648–54, discussion 654-5. PMC 1422490. PMID 11981210.